SynthesisHippocampus2022
A meta-analysis of the relation between hippocampal volume and memory ability in typically developing children and adolescents.
Synthesis in Hippocampus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- A meta-analysis of the relation between hippocampal volume and memory ability in typically developing children and adolescents.Hippocampus · 2022Pooled it
- Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: findings from the Rhineland Study.Molecular psychiatry · 2026Article
- Ambient pollution components and sources are associated with hippocampal architecture and memory in pre-adolescents.BMC medicine · 2026Article
- Trajectories of hippocampal subregion development in the first years of life and their association with school-aged episodic memory outcomes.bioRxiv : the preprint server for biology · 2026Article
- Safety-relevant experience reshapes neural codes for ambiguous threat in adolescents.Social cognitive and affective neuroscience · 2026Article
- Structural Learning in Autistic and Non-Autistic Children: A Replication and Extension.Journal of autism and developmental disorders · 2026Article
- Spontaneous reinstatement of episodic memories in the developing human brain.bioRxiv : the preprint server for biology · 2025Article
- Scene construction deficits in adolescent PTSD are in sensory, rather than spatial, imagery.Frontiers in psychology · 2025Article
- Brain reserve in memory regions is associated with the preservation of autobiographical memories after electroconvulsive therapy.Frontiers in psychiatry · 2025Article
- Region-Specific Brain Volume Changes Emerge in Adolescence in the Valproic Acid Model of Autism and Parallel Human Findings.Developmental neuroscience · 2025Article
- Effects of glycaemic control on memory performance, hippocampal volumes and depressive symptomology.Diabetology & metabolic syndrome · 2024Article
- Revealing complexity: segmentation of hippocampal subfields in adolescents with major depressive disorder reveals specific links to cognitive dysfunctions.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Association of retinal nerve layers thickness and brain imaging in healthy young subjects from the i-Share-Bordeaux study.Human brain mapping · 2023Article
- Using an episodic specificity induction to improve children's future thinking.Frontiers in psychology · 2023Article
- Early emotional caregiving environment and associations with memory performance and hippocampal volume in adolescents with prenatal drug exposure.Frontiers in behavioral neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Memory is supported by a network of brain regions, with the hippocampus serving a critical role in this cognitive process. Previous meta-analyses on the association between hippocampal structure and memory have largely focused on adults. Multiple studies have since suggested that hippocampal volume is related to memory performance in children and adolescents; however, the strength and direction of this relation varies across reports, and thus, remains unclear. To further understand this brain-behavior relation, we conducted a meta-analysis to investigate the association between hippocampal volume (assessed as total volume) and memory during typical development. Across 25 studies and 61 memory outcomes with 1357 participants, results showed a small, but significant, positive association between total hippocampal volume and memory performance. Estimates of the variability across studies in the relation between total volume and memory were not explained by differences in memory task type (delayed vs. immediate; relational vs. nonrelational), participant age range, or the method of normalization of hippocampal volumes. Overall, findings suggest that larger total hippocampal volume relates to better memory performance in children and adolescents and that this relation is similar across the memory types and age ranges assessed. To facilitate enhanced generalization across studies in the future, we discuss considerations for the field moving forward.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.