Evidence map›Paper›PMID 35301461›Full record

ArticleEuropean journal of clinical nutrition2022

Roseburia, a decreased bacterial taxon in the gut microbiota of patients suffering from anorexia nervosa.

Stanislas Mondot, Laurine Lachkar, Joël Doré, Hervé M Blottière, Mouna Hanachi

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In one paragraph

Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stanislas MondotParis-Saclay university, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France. stanislas.mondot@inrae.fr.ORCID 0000-0003-3668-3168
Laurine LachkarNutrition Unit, Paul Brousse University Hospital, Villejuif; Assistance Publique-Hôpitaux de Paris, Paris, France.
Joël DoréParis-Saclay university, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France.ORCID 0000-0002-8756-0718
Hervé M BlottièreParis-Saclay university, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France.ORCID 0000-0002-8390-0607
Mouna HanachiParis-Saclay university, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France. mouna.hanachi@aphp.fr.ORCID 0000-0002-7228-8723
AgroParisTech · FRMicrobiologie de l’alimentation au service de la santé · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anorexia nervosa (AN) is a severe eating disorder which can lead to malnutrition and life threatening complications with high mortality rates. We designed our analysis to identify gut microbial taxa differentially abundant between AN and HC across different 16S rRNA gene datasets. We identified a reduced abundance, diversity and richness of Roseburia genus in the microbiota of patients with AN. Cares leading to partial recovery of patients with AN during hospitalization did not restore Roseburia to the levels of HC. AN dietary habit, either purgative or restrictive, did not affect Roseburia abundance. Roseburia genus and related species abundance were correlated with different health host metabolic markers. Roseburia species are key functional taxa in the human gut microbiome. Low gut Roseburia levels have been linked with other human pathologies. Our study highlights Roseburia species as a major decreased component in the gut of patients with AN.

Indexed as

Anorexia NervosaGastrointestinal MicrobiomeBacteriaCatharticsFecesHumansRNA, Ribosomal, 16SCatharticsRNA, Ribosomal, 16S

Identifiers

PMID35301461
OpenAlexW4220665122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.