ArticleScientific reports2022
Treatment of ocular tumors through a novel applicator on a conventional proton pencil beam scanning beamline.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Dosimetric feasibility of carbon-ion radiotherapy for ocular melanomas with local effect model-based treatment planning system.Journal of radiation research · 2026Article
- An operational key performance indicator framework and reference data from a multi-room pencil beam scanning proton therapy center.PloS one · 2026Article
- Implementing ocular treatment with pencil beam scanning: the FHCC experience.Radiation oncology (London, England) · 2025Article
- Proton Therapy for Uveal Melanoma on a Pencil Beam Scanning Gantry.Advances in radiation oncology · 2025Article
- Gantry-based pencil beam scanning proton therapy for uveal melanoma: IMPT versus proton arc therapy.Radiation oncology (London, England) · 2025Article
- Radiotherapy of Orbital and Ocular Adnexa Lymphoma: Literature Review and University of Catania Experience.Cancers · 2023Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Treatment of ocular tumors on dedicated scattering-based proton therapy systems is standard afforded due to sharp lateral and distal penumbras. However, most newer proton therapy centers provide pencil beam scanning treatments. In this paper, we present a pencil beam scanning (PBS)-based ocular treatment solution. The design, commissioning, and validation of an applicator mount for a conventional PBS snout to allow for ocular treatments are given. In contrast to scattering techniques, PBS-based ocular therapy allows for inverse planning, providing planners with additional flexibility to shape the radiation field, potentially sparing healthy tissues. PBS enables the use of commercial Monte Carlo algorithms resulting in accurate dose calculations in the presence of heterogeneities and fiducials. The validation consisted of small field dosimetry measurements of point doses, depth doses, and lateral profiles relevant to ocular therapy. A comparison of beam properties achieved through the applicator against published literature is presented. We successfully showed the feasibility of PBS-based ocular treatments.
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Registered trials
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