Evidence map›Paper›PMID 35301251›Full record

ArticleThe European respiratory journal2022

Lung function from school age to adulthood in primary ciliary dyskinesia.

Florian S Halbeisen, Eva S L Pedersen, Myrofora Goutaki, Ben D Spycher, Israel Amirav, Mieke Boon, Malena Cohen-Cymberknoh, Suzanne Crowley, Nagehan Emiralioglu, Eric G Haarman and 15 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The European respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03517865 (International Primary Ciliary Dyskinesia Cohort), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03517865 active not recruitingnot on this map

International Primary Ciliary Dyskinesia Cohort

TypeobservationalSponsorUniversity of BernRan2013 to 2080Enrolled3,400ConditionsPrimary Ciliary Dyskinesia, Kartagener Syndrome
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Nutrition and growth of primary ciliary dyskinesia patients: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Pulmonary exacerbations in primary ciliary dyskinesia.European journal of pediatrics · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Advances in respiratory medicine · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Primary Ciliary Dyskinesia.CHEST pulmonary · 2023
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 18 institutions in 15 countries.

Florian S HalbeisenInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Eva S L PedersenInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0003-0293-9954
Myrofora GoutakiInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-8036-2092
Ben D SpycherInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Israel AmiravThe PCD Israeli Consortium.ORCID 0000-0002-6917-5285
Mieke BoonDept of Paediatrics, University Hospital Gasthuisberg, Leuven, Belgium.
Malena Cohen-CymberknohPediatric Pulmonology Unit and Cystic fibrosis Center, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Suzanne CrowleyPaediatric Dept of Allergy and Lung Diseases, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-2786-8718
Nagehan EmiraliogluDept of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.ORCID 0000-0002-1405-8401
Eric G HaarmanDept of Pediatric Pulmonology, Emma Children's Hospital, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Bulent KaradagDept of Pediatric Pulmonology, Marmara University, School of Medicine, Istanbul, Turkey.
Cordula Koerner-RettbergDept of Paediatric Pneumology, University Children's Hospital of Ruhr University Bochum, Bochum, Germany.
Philipp LatzinDivision of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-5239-1571
Michael R LoebingerHost Defence Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, UK.
Jane S LucasPrimary Ciliary Dyskinesia Centre, NIHR Respiratory Biomedical Research Centre, University of Southampton and University Hospital, Southampton, UK.ORCID 0000-0001-8701-9975
Henryk MazurekDept of Pneumonology and Cystic Fibrosis, Institute of Tuberculosis and Lung Disorders, Rabka -‌ Zdrój, Poland.
Lucy MorganDept of Respiratory Medicine, Concord Hospital Clinical School, University of Sydney, Sydney, Australia.ORCID 0000-0001-6389-1953
June MarthinDanish PCD Centre Copenhagen, Paediatric Pulmonary Service, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0002-4420-3091
Petr PohunekPaediatric Dept, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.ORCID 0000-0003-4557-2515
Francesca SantamariaDept of Translational Medical Sciences, Federico II University, Napoli, Italy.ORCID 0000-0002-9375-7429
Nicolaus SchwerkClinic for Paediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
Guillaume ThouveninPediatric Pulmonology Dept, APHP Hôpital Trousseau, Sorbonne Université, Centre de Recherche Saint-Antoine (CRSA), Inserm UMR_S938, Paris, France.ORCID 0000-0003-0528-5458
Panayiotis YiallourosMedical School, University of Cyprus, Nicosia, Cyprus.
Kim G NielsenDanish PCD Centre Copenhagen, Paediatric Pulmonary Service, Copenhagen University Hospital, Copenhagen, Denmark.
Claudia E KuehniInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland claudia.kuehni@ispm.unibe.ch.ORCID 0000-0001-8957-2002
University of Bern · CHThe University of Sydney · AUCharles University · CZCystic Fibrosis Research Foundation · ITEmma Kinderziekenhuis · NLFederico II University Hospital · ITHacettepe University · TRHebrew University of Jerusalem · ILInserm · FRMarmara University · TRMedizinische Hochschule Hannover · DEOslo University Hospital · NORoyal Brompton & Harefield NHS Foundation Trust · GBUniversity Hospitals of the Ruhr-University of Bochum · DEUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Alberta · CAUniversity of Copenhagen · DKUniversity of Cyprus · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary ciliary dyskinesia (PCD) presents with symptoms early in life and the disease course may be progressive, but longitudinal data on lung function are scarce. This multinational cohort study describes lung function trajectories in children, adolescents and young adults with PCD. We analysed data from 486 patients with repeated lung function measurements obtained between the age of 6 and 24 years from the International PCD Cohort and calculated z-scores for forced expiratory volume in 1 s (FEV

Indexed as

Ciliary Motility DisordersAdolescentAdultChildCohort StudiesForced Expiratory VolumeHumansLungVital CapacityYoung Adult

Identifiers

PMID35301251
PMCPMC9582507
OpenAlexW4220905699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.