Evidence map›Paper›PMID 35301221›Full record

ArticleeNeuro

Temporally and Spatially Localized PKA Activity within Learning and Memory Circuitry Regulated by Network Feedback.

James C Sears, Kendal Broadie

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Active zone plasticity couples sleep need to presynaptic hypophosphorylation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. cAMP/PKA signaling regulates TDP-43 aggregation and mislocalization.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Use-Dependent, Untapped Dual Kinase Signaling Localized in Brain Learning Circuitry.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James C SearsDepartment of Biological Sciences, Vanderbilt University and Medical Center, Nashville, TN 37235.ORCID 0000-0003-2918-2429
Kendal BroadieDepartment of Biological Sciences, Vanderbilt University and Medical Center, Nashville, TN 37235 kendal.broadie@vanderbilt.edu.ORCID 0000-0003-3783-6023
Vanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Genetic and Developmental Analyses of Fragile X SyndromeR01MH084989 · NIMH · VANDERBILT UNIVERSITY · PI BROADIE, KENDAL · 2009 to 2021
$5.5M
Genetic and Developmental Analyses of Fragile X Mental Retardation ProteinR56MH084989 · NIMH · VANDERBILT UNIVERSITY · PI BROADIE, KENDAL · 2023 to 2023
$516k
NICHD NIH HHS P50 HD103537NIMH NIH HHS R01 MH084989NIMH NIH HHS R56 MH084989
6 · The paper itself

Abstract

Dynamic functional connectivity within brain circuits requires coordination of intercellular signaling and intracellular signal transduction. Critical roles for cAMP-dependent protein kinase A (PKA) signaling are well established in the

Indexed as

Drosophila ProteinsMushroom BodiesAnimalsDrosophilaFeedbackFemaleLearningMaleDrosophila ProteinsDrosophilaFMRPKenyon cellMeng-Pomushroom bodyneurobeachin

Identifiers

PMID35301221
PMCPMC8982635
OpenAlexW4220662083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.