Evidence map›Paper›PMID 35301127›Full record

ArticleJournal of vascular and interventional radiology : JVIR2022

Evaluating Radioactive Analogs of Doxorubicin to Quantify ChemoFilter Binding and Whole-Body Positron Emission Tomography/Magnetic Resonance Imaging for Drug Biodistribution.

Parth Kumar, Colin Yee, Joseph E Blecha, Thomas R Hayes, Bridget F Kilbride, Carol Stillson, Aaron D Losey, Eric Mastria, Caroline D Jordan, Tony L Huynh and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. 3D Printed Biosponge Adsorbers for Capturing Toxic Chemotherapy DrugsACS biomaterials science & engineering · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Parth KumarDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Colin YeeDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Joseph E BlechaDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Thomas R HayesDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Bridget F KilbrideDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Carol StillsonDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Aaron D LoseyDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Eric MastriaDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Caroline D JordanDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Tony L HuynhDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Terilyn MooreDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Mark W WilsonDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Henry F VanBrocklinDepartment of Radiology & Biomedical Imaging, University of California, San Francisco.
Steven W HettsDepartment of Radiology & Biomedical Imaging, University of California, San Francisco. Electronic address: Steven.Hetts@ucsf.edu.
University of California, San Francisco · US

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
Endovascular Magnetic Catheter for Interventional MRIR01EB012031 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM, MARTIN, ALASTAIR J · 2011 to 2021
$4.8M
Endovascular ChemoFilter to Reduce Doxorubicin Toxicity during Intra-Arterial ChemotherapyR42CA265316 · NCI · FILTRO MEDICAL INC. · PI HETTS, STEVEN WILLIAM · 2021 to 2024
$2.6M
Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce ToxicityR01CA194533 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HETTS, STEVEN WILLIAM · 2015 to 2019
$2.6M
NCI NIH HHS R01 CA194533NCI NIH HHS R42 CA265316NIBIB NIH HHS R01 EB012031NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

purposeTo evaluate radiolabeled doxorubicin (Dox) analogs as tracers of baseline Dox biodistribution in vivo during hepatic intra-arterial chemotherapy and to assess the efficacy of ChemoFilter devices to bind Dox in vitro. MATERIALS AND

methodsIn an in vitro static experiment, [fluorine-18]N-succinimidyl 4-fluorobenzoate ([

resultsIn the in vitro static experiment, [

conclusions[

Indexed as

DoxorubicinPositron-Emission TomographyAnimalsHepatic ArteryHumansMagnetic Resonance ImagingSwineTissue DistributionDoxorubicin

Identifiers

PMID35301127
PMCPMC9156544
OpenAlexW4220851393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.