ArticleJournal of controlled release : official journal of the Controlled Release Society2022
A nanovaccine for enhancing cellular immunity via cytosolic co-delivery of antigen and polyIC RNA.
Open access · greenAbstract read
In one paragraph
Article in Journal of controlled release : official journal of the Controlled Release Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Multifunctional nanotherapeutics for targeted modulation of endoplasmic reticulum stress to potentiate cancer therapy.Asian journal of pharmaceutical sciences · 2026Review
- Thermoreversibly assembled polymersomes for highly efficient loading, processing and delivery of protein and siRNA biologics.Nature biomedical engineering · 2026Article
- Nanoparticle Delivery of Alu RNA Adjuvants Enhances Vaccine Immunogenicity.ACS applied materials & interfaces · 2025Article
- Emerging Cationic Nanovaccines.Pharmaceutics · 2024Review
- Nanocarrier design for pathogen-inspired innate immune agonist delivery.Trends in immunology · 2024Review
- Engineering customized nanovaccines for enhanced cancer immunotherapy.Bioactive materials · 2024Review
- Engineering endosomolytic nanocarriers of diverse morphologies using confined impingement jet mixing.Nanoscale · 2023Article
- Nanoparticle Delivery of Immunostimulatory Alu RNA for Cancer Immunotherapy.Cancer research communications · 2023Article
- Instructional materials that control cellular activity through synthetic Notch receptors.Biomaterials · 2023Article
- Dual-Responsive Glycopolymers for Intracellular Codelivery of Antigen and Lipophilic Adjuvants.Molecular pharmaceutics · 2022Article
- Nanovaccines: Merits, and diverse roles in boosting antitumor immune responses.Human vaccines & immunotherapeutics · 2022Review
- Efficient Anti-Tumor Immunotherapy Using Tumor Epitope-Coated Biodegradable Nanoparticles Combined With Polyinosinic-Polycytidylic Acid and an Anti-PD1 Monoclonal Antibody.Immune network · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Carcia S CarsonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Kyle W BeckerDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Kyle M GarlandDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Hayden M PagendarmDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Payton T StoneDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Karan AroraDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Lihong Wang-BishopDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Jessalyn J BaljonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA; Department of Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212, USA.
Lorena D CruzDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Sebastian JoyceDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
John T WilsonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address: john.t.wilson@vanderbilt.edu.
Vanderbilt University · USVA Tennessee Valley Healthcare System · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MChemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0MIntegrated Training in Engineering and DiabetesT32DK101003 · NIDDK · VANDERBILT UNIVERSITY · PI Jamey D. Young · 2014 to 2026
$3.9MEngineered Vaccines for Neoantigen Targeted Cancer ImmunotherapyR01CA266767 · NCI · VANDERBILT UNIVERSITY · PI John Tanner Wilson · 2022 to 2026
$2.4MHead & Neck Cancer Neoantigen Characterization & Therapeutic TargetingR01DE027749 · NIDCR · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JOYCE, SEBASTIAN · 2018 to 2022
$2.3MMolecular Basis of CD1D and Natural Killer T Cell FunctionR01AI137082 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JOYCE, SEBASTIAN · 2019 to 2022
$2.1MEngineered Nanoparticles for Protective Subunit Vaccine Delivery and DiscoveryR21AI121626 · NIAID · VANDERBILT UNIVERSITY · PI WILSON, JOHN TANNER · 2016 to 2017
$418kAn Engineered Nanocarrier Platform for Enhancing Immune Responses to Neoantigen-Targeted Cancer VaccinesF31CA257275 · NCI · VANDERBILT UNIVERSITY · PI BALJON, JESSALYN J · 2021 to 2023
$120kBLRD Research Career Scientist Award ApplicationIK6BX004595 · VA · VETERANS HEALTH ADMINISTRATION · PI JOYCE, SEBASTIAN · 2019 to 2025
–Vaccinating at Mucosal Surfaces with Nanoparticle Conjugated Antigen and AdjuvantI01BX001444 · VA · VETERANS HEALTH ADMINISTRATION · PI JOYCE, SEBASTIAN · 2014 to 2022
–BLRD VA I01 BX001444BLRD VA I01 BX006010BLRD VA IK6 BX004595NCI NIH HHS F31 CA257275NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA266767NIAID NIH HHS R01 AI137082NIAID NIH HHS R21 AI121626NIDCR NIH HHS R01 DE027749NIDDK NIH HHS P30 DK058404NIDDK NIH HHS T32 DK101003NIGMS NIH HHS T32 GM065086
Abstract
Traditional approaches to cancer vaccines elicit weak CD8
Indexed as
Cancer VaccinesNanoparticlesAdjuvants, ImmunologicAnimalsAntigensCD8-Positive T-LymphocytesCytosolDendritic CellsImmunity, CellularMiceOvalbuminRNAAdjuvants, ImmunologicAntigensCancer VaccinesOvalbuminRNACancer vaccineEndosomal escapeNucleic acid adjuvantpH-responsivePolyICT cells
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.