Evidence map›Paper›PMID 35301014›Full record

SynthesisThe Journal of infection2022

The effect of canakinumab on clinical outcomes in patients with COVID-19: A meta-analysis.

Guangyu Ao, Yushu Wang, Toni Li, Carolyn Tran, Qing Yang

Open access · hybridAbstract readLetterMeta-Analysis
In one paragraph

Synthesis in The Journal of infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Macrophage activation syndrome in Sepsis: from pathogenesis to clinical management.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  3. NLRP3 Inflammasomes: Dual Function in Infectious Diseases.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Guangyu AoDepartment of Nephrology, Chengdu First People's Hospital, Chengdu, Sichuan, China.
Yushu WangChengdu West China Clinical Research Center, Chengdu, Sichuan, China.
Toni LiSchool of Medicine, Queen's University, Kingston, Canada.
Carolyn TranSchulich School of Medicine and Dentistry, Western University, London, Canada.
Qing YangDepartment of Cardiology, West China Hospital, Sichuan University, No.37 Guoxue Lane, Wuhou District, Chengdu, Sichuan 610044, China. Electronic address: qingyang@scu.edu.cn.
Queen's University · CAWest China Hospital of Sichuan University · CNWest China Medical Center of Sichuan University · CNWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentAntibodies, Monoclonal, HumanizedHumansSARS-CoV-2Antibodies, Monoclonal, HumanizedcanakinumabCanakinumabCOVID-19MortalitySARS-CoV-2

Identifiers

PMID35301014
PMCPMC8920470
OpenAlexW4221106942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.