Evidence map›Paper›PMID 35300945›Full record

SynthesisBiomedical journal2021

Bladder volume reproducibility after water consumption in patients with prostate cancer undergoing radiotherapy: A systematic review and meta-analysis.

Hsiao-Hsuan Chen, Pei-Tzu Lin, Liang-Tseng Kuo, Kun-Sheng Lin, Chiung-Chen Fang, Ching-Chi Chi

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Biomedical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hsiao-Hsuan ChenDepartment of Radiation Therapy, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan; Center for Evidence-Based Medicine, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Pei-Tzu LinCenter for Evidence-Based Medicine, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan; Department of Pharmacy, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Liang-Tseng KuoCenter for Evidence-Based Medicine, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan; Department of Orthopaedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Kun-Sheng LinDepartment of Radiation Therapy, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Chiung-Chen FangDepartment of Radiation Therapy, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Ching-Chi ChiDepartment of Dermatology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address: chingchi@cgmh.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo minimize toxicity due to radiotherapy in patients with prostate cancer, high bladder volume reproducibility is essential. Water consumption is often used to increase bladder volume reproducibility, but the optimal amount of water required to be consumed remains unclear. We aimed to analyzed the relationship between water consumption and bladder volume reproducibility in patients undergoing radiotherapy for prostate cancer.

methodsWe conducted a systematic review and meta-analysis of randomized controlled trials and cohort studies that assessed bladder volume change after water consumption in patients with prostate cancer undergoing radiotherapy. MEDLINE, Embase, and Cochrane Central Register of Controlled Trials were searched for relevant studies published from database inception up until July 4, 2020. The Newcastle-Ottawa Scale was used to evaluate the risk of bias in the included studies. The outcome was the mean difference (MD) of bladder volume after water consumption, evaluated through meta-analysis using a random-effects model.

resultsTen cohort studies and one randomized controlled trial with a total of 417 patients were included. For 300-400 ml water consumption, the bladder volume MD between during treatment and at computer tomography-simulation (95% confidence interval [CI]) was -11.97 (-51.68 to 27.74), was -45.99 (-82.85 to -9.13) for 500-540 ml water consumption and -45.92 (-78.86 to -12.98) for water consumption until full-bladder sensation was reached.

conclusionConsuming 300-400 ml of water potentially leads to the best bladder volume reproducibility; moreover, the higher the water consumption volume, the lower the bladder volume reproducibility.

Indexed as

DrinkingProstatic NeoplasmsHumansMaleRandomized Controlled Trials as TopicReproducibility of ResultsUrinary BladderWaterWaterBladder volumeProstate cancerRadiotherapyReproducibility

Identifiers

PMID35300945
PMCPMC9068550

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.