Evidence map›Paper›PMID 35300894›Full record

ArticleNeuromuscular disorders : NMD2022

Leveraging cardiac magnetic resonance imaging to assess skeletal muscle progression in Duchenne muscular dystrophy.

Jacob A Kaslow, Andrew G Sokolow, Thomas Donnelly, Maciej S Buchowski, Bruce M Damon, Larry W Markham, W Bryan Burnette, Jonathan H Soslow

Open access · greenAbstract read
In one paragraph

Article in Neuromuscular disorders : NMD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jacob A KaslowDepartment of Pediatrics, Division of Pediatric Pulmonary, Vanderbilt University Medical Center, 2200 Children's Way, Doctors' Office Tower 11215, Nashville, TN 37232, USA. Electronic address: jacob.a.kaslow@vumc.org.
Andrew G SokolowDepartment of Pediatrics, Division of Pediatric Pulmonary, Vanderbilt University Medical Center, 2200 Children's Way, Doctors' Office Tower 11215, Nashville, TN 37232, USA.
Thomas DonnellyDepartment of Pediatrics, Thomas P Graham Jr. Division of Pediatric Cardiology, Vanderbilt University Medical Center, 2200 Children's Way, Doctors' Office Tower 5230, Nashville, TN 37232, USA.
Maciej S BuchowskiDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University Medical Center, 1161 21st Ave S, Nashville, TN 37232 USA.
Bruce M DamonDepartments of Radiology and Radiological Sciences, Molecular Physiology and Biophysics, and Biomedical Engineering, Vanderbilt University Medical Center, 1161 21st Ave S, AA-3105 Medical Center North, Nashville, TN, USA.
Larry W MarkhamDepartment of Pediatrics, Division of Cardiology, Riley Hospital for Children at Indiana University Health, 705 Riley Hospital Drive, RR 1134, Indianapolis, IN 46202, USA.
W Bryan BurnetteDivision of Pediatric Neurology, Vanderbilt University Medical Center, 2200 Children's Way, Doctors' Office Tower 9th floor, Nashville, TN 37232, USA.
Jonathan H SoslowDepartment of Pediatrics, Thomas P Graham Jr. Division of Pediatric Cardiology, Vanderbilt University Medical Center, 2200 Children's Way, Doctors' Office Tower 5230, Nashville, TN 37232, USA.
Vanderbilt University Medical Center · USIndiana University Health · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
Prospective Development of a Multimodal Biomaker Platform for Predictive Risk Stratification of Cardiac Disease in Duchenne Muscular DystrophyR01FD006649 · FDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2019 to 2024
$2.5M
Quantitative Assessment of Cardiac Disease in Duchenne Muscular DystrophyK23HL123938 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2014 to 2018
$829k
Development of a Multimodal Biomaker Platform for Predictive Risk Stratification of Cardiac Disease in Duchenne Muscular DystrophyR56HL141248 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2018 to 2018
$769k
FDA HHS R01 FD006649NCATS NIH HHS UL1 TR002243NHLBI NIH HHS K23 HL123938NHLBI NIH HHS R56 HL141248NHLBI NIH HHS T32 HL087738NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is characterized by muscle deterioration and progressive weakness. As a result, patients with DMD have significant cardiopulmonary morbidity and mortality that worsens with age and loss of ambulation. Since most validated muscle assessments require ambulation, new functional measures of DMD progression are needed. Despite several evaluation methods available for monitoring disease progression, the relationship between these measures is unknown. We sought to assess the correlation between imaging metrics obtained from cardiac magnetic resonance imaging (CMR) and functional assessments including quantitative muscle testing (QMT), spirometry, and accelerometry. Forty-nine patients with DMD were enrolled and underwent CMR, accelerometry and QMT at baseline, 1-year and 2-year clinic visits with temporally associated pulmonary function testing obtained from the medical record. Imaging of the upper extremity musculature (triceps and biceps) demonstrated the most robust correlations with accelerometry (p<0.03), QMT (p<0.02) and spirometry (p<0.01). T

Indexed as

Muscular Dystrophy, DuchenneDisease ProgressionHeartHumansMagnetic Resonance ImagingMuscle, SkeletalDuchenne muscular dystrophy, MRI, spirometry, accelerometry, quantitative muscle testing

Identifiers

PMID35300894
PMCPMC9117482
OpenAlexW4210397648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.