Evidence map›Paper›PMID 35300390›Full record

ArticleLancet regional health. Americas2022

Prevalence of parkinsonism and Parkinson disease in urban and rural populations from Latin America: A community based study.

Jorge J Llibre-Guerra, Matthew Prina, Ana Luisa Sosa, Daisy Acosta, Ivonne Z Jimenez-Velazquez, Mariella Guerra, Aquiles Salas, Juan C Llibre-Guerra, Adolfo Valvuerdi, Geeske Peeters and 5 more

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta-Analysis.Movement disorders : official journal of the Movement Disorder Society · 2024
    Pooled it
  3. Article
  4. Observational
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  6. Review
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  11. Barriers and Facilitators to Accessing Healthcare for People With Parkinson's Disease in Latin America: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  12. Article
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  18. Article
  19. Epidemiology of Parkinson's Disease: An Update.Current neurology and neuroscience reports · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jorge J Llibre-GuerraDepartment of Neurology, Washington University School of Medicine in St. Louis, USA.
Matthew PrinaHealth Service and Population Research Department, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.
Ana Luisa SosaLaboratory of the Dementias, National Institute of Neurology and Neurosurgery of Mexico, National Autonomous University of Mexico, Mexico City, Mexico.
Daisy AcostaUniversidad Nacional Pedro Henriquez Ureña (UNPHU), Internal Medicine Department, Geriatric Section, Santo Domingo, Dominican Republic.
Ivonne Z Jimenez-VelazquezInternal Medicine Department, Geriatrics Program, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.
Mariella GuerraInstituto de la Memoria Depresion y Enfermedades de Riesgo IMEDER, Lima, Perú.
Aquiles SalasMedicine Department, Caracas University Hospital, Faculty of Medicine, Universidad Central de Venezuela, Caracas, Venezuela.
Juan C Llibre-GuerraDepartment of Neurology, Hospital del Mar, Barcelona, Spain.
Adolfo ValvuerdiMedical University of Matanzas, Matanzas, Cuba.
Geeske PeetersRadboud Institute of Health Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands.
Ellen ZiegemeierDepartment of Neurology, Washington University School of Medicine in St. Louis, USA.
Isaac AcostaLaboratory of the Dementias, National Institute of Neurology and Neurosurgery of Mexico, National Autonomous University of Mexico, Mexico City, Mexico.
Caroline TannerDepartment of Neurology, Weill Institute for Neurosciences, University of San Francisco, California, USA.
Jorge JuncosDepartment of Neurology, Emory University School of Medicine.
Juan J Llibre RodriguezFacultad de Medicina Finlay-Albarran, Medical University of Havana, Havana, Cuba.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Age and gender specific prevalence rates for parkinsonism and Parkinson's disease (PD) are important to guide research, clinical practice, and public health planning; however, prevalence estimates in Latin America (LatAm) are limited. We aimed to estimate the prevalence of parkinsonism and PD and examine related risk factors in a cohort of elderly individuals from Latin America (LatAm). Methods: Data from 11,613 adults (65+ years) who participated in a baseline assessment of the 10/66 study and lived in six LatAm countries were analyzed to estimate parkinsonism and PD prevalence. Crude and age-adjusted prevalence were determined by sex and country. Diagnosis of PD was established using the UK Parkinson's Disease Society Brain Bank's clinical criteria. Findings: In this cohort, the prevalence of parkinsonism was 8.0% (95% CI 7.6%-8.5%), and the prevalence of PD was 2.0% (95% CI 1.7%-2.3%). PD prevalence increased with age from 1.0 to 3.5 (65-69vs. 80 years or older, Interpretation: The reported prevalence of PD in LatAm is similar to reports from high-income countries (HIC). A significant proportion of cases with PD did not have a previous diagnosis, nor did they seek any medical or neurological attention. These findings underscore the need to improve public health programs for populations currently undergoing rapid demographic aging and epidemiological transition. Funding: The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Indexed as

Latin AmericaParkinsonismParkinson's diseasePrevalenceRisk factors

Identifiers

PMID35300390
PMCPMC8920908

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.