Evidence map›Paper›PMID 35300333›Full record

ReviewFrontiers in immunology2022

Anti-IgLON5 Disease - The Current State of Knowledge and Further Perspectives.

Natalia Madetko, Weronika Marzec, Agata Kowalska, Dominika Przewodowska, Piotr Alster, Dariusz Koziorowski

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Suspected encephalitis in adults.Practical neurology · 2026
    Review
  4. eLife · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. bioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. IgLON5-IgG: Innocent Bystander or Perpetrator?International journal of molecular sciences · 2024
    Review
  18. Article
  19. Diagnosis and Management of Progressive Corticobasal Syndrome.Current treatment options in neurology · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia MadetkoDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Weronika MarzecStudents' Scientific Circle of the Department of Neurology, Medical University of Warsaw, Warsaw, Poland.
Agata KowalskaStudents' Scientific Circle of the Department of Neurology, Medical University of Warsaw, Warsaw, Poland.
Dominika PrzewodowskaStudents' Scientific Circle of the Department of Neurology, Medical University of Warsaw, Warsaw, Poland.
Piotr AlsterDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Dariusz KoziorowskiDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-IgLON5 disease is a relatively new neurological entity with the first cases reported in 2014. So far, less than 70 articles on this topic have been published. Due to its unspecific symptomatology, diverse progression, novelty and ambiguous character, it remains a difficulty for both clinical practitioners and scientists. The aim of this review is to summarize the current knowledge concerning anti-IgLON5 disease; mechanisms underlying its cause, symptomatology, clinical progression, differential diagnosis and treatment, which could be helpful in clinical practice and future research.

Indexed as

EncephalitisHashimoto DiseaseCell Adhesion Molecules, NeuronalHumansCell Adhesion Molecules, Neuronalautoimmune diseaseIgLON5 antibodiesIgLON5 diseaseneurodegenerationneuroinflammation

Identifiers

PMID35300333
PMCPMC8921982

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.