Evidence map›Paper›PMID 35300269›Full record

ArticleInternational journal of health sciences

Modulation of mice immune responses against Schistosoma mansoni infection with anti-schistosomiasis drugs: Role of interleukin-4 and interferon-gamma.

Osama F Sharaf, Ahmed A Ahmed, Asmaa F Ibrahim, Ali Shariq, Abdullah S Alkhamiss, Ruqaih Alghsham, Sami A Althwab, Sultan A Alghaniam, Fahad A Alhumaydhi, Rana Alghamdi and 5 more

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PubMed Full text at PMC
In one paragraph

Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Osama F SharafDepartment of Clinical and Molecular Parasitology, National Liver Institute, Menoufia University, Shibin Al kom, Al Menoufia, Egypt.
Ahmed A AhmedResearch Center, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Asmaa F IbrahimDepartment of Clinical and Molecular Parasitology, National Liver Institute, Menoufia University, Shibin Al kom, Al Menoufia, Egypt.
Ali ShariqDepartment of Microbiology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Abdullah S AlkhamissDepartment of Pathology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Ruqaih AlghshamDepartment of Pathology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Sami A AlthwabDepartment of Clinical Nutrition, Qassim Health Affairs, Ministry of Health, Buraidah, Saudi Arabia.
Sultan A AlghaniamDepartment of Food Science and Human Nutrition, College of Agriculture and Veterinary Medicine, Qassim University, Buraidah, Saudi Arabia.
Fahad A AlhumaydhiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah, Saudi Arabia.
Rana AlghamdiDepartment of Chemistry, Science and Arts College, Rabigh Campus, King Abdulaziz University, Jeddah, Saudi Arabia.
Ahmad AlshomarDepartment of Medicine, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Tasleem AlabdullatifDepartment of Pathology, Faculty of Medicine, Northern Border University, Arar, Saudi Arabia.
Abdulrahman AlkhulayfiDepartment of Pathology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Abdulrhman A AlghunaimPrivate Health Sector, Qassim Health, Jeddah, Saudi Arabia.
Waleed Al AbdulmonemDepartment of Pathology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
Qassim University · SABuraydah Colleges · SAKing Abdulaziz University · SANorthern Border University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Methods: Laboratory bred female albino mice ( Results: Anti-schistosomiasis drugs ART and ARA increased the levels of Th2 cytokine IL-4 ( Conclusions: These findings indicated that anti-schistosomiasis drugs ART, ARA, and PZQ play a role in the modulation of expression of Th2 cytokines. Whereas, only PZQ may play a role in the modulation of Th1 cytokines. These findings provide a scope for the formulation of novel anti-schistosomal drugs as well as in the therapeutic management of patients infected with

Indexed as

Arachidonic acidartemisinininterferon-gammainterleukin-4nifedipinepraziquantelSchistosoma mansoni

Identifiers

PMID35300269
PMCPMC8905037
OpenAlexW4221155176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.