Evidence map›Paper›PMID 35300216›Full record

ArticleJournal of inflammation research2022

The Mutation of

Dan Guo, Lemin Hong, Hao Ji, Yuwen Jiang, Ling Lu, Xinfeng Wang, Hongming Huang

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dan Guo *Department of Hematology, The Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China.
Lemin Hong *Department of Hematology, The Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China.ORCID 0000-0003-0530-1622
Hao Ji *Department of Urology, Tumor Hospital Affiliated to Nantong University, Nantong, People's Republic of China.
Yuwen JiangDepartment of Hematology, The Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China.
Ling LuDepartment of Hematology, The Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China.
Xinfeng WangDepartment of Hematology, The Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China.
Hongming HuangDepartment of Hematology, The Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China.ORCID 0000-0001-9695-4674
Nantong University · CNNantong Tumor Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Primary testicular diffuse large B-cell lymphoma (PT-DLBCL) is a rare and aggressive form of mature B-cell lymphoma commonly found in elder males, but its genetic features are poorly understood. In this study, we had performed target-sequencing of 360 lymphoma-related genes on 76 PT-DLBCL patients with a median age of 65 (33-89). Our data provide a comprehensive understanding of the landscape of mutations in a small subset of PT-DLBCL. Methods: A total of 76 PT-DLBCL patients were sequenced, and their clinical data and follow-up data were collected. The relationship between mutated genes, clinical data and prognosis and survival of PT-DLBCL patients was retrospectively analyzed by statistical software. Results: We observed a median of 15 protein-altering variants per patient in our data and was identified recurrent oncogenic mutations of 360 lymphoma-related genes involved in PT-DLBCL, including Conclusion: In conclusion, our results revealed genomic characterization of PT-DLBCL, and the mutation of

Indexed as

BTG2genetic mutationprimary testicular diffuse large B-cell lymphomaprognosissurvival

Identifiers

PMID35300216
PMCPMC8923029
OpenAlexW4220773363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.