ArticleFrontiers in aging neuroscience2022
Mild Cognitive Impairment Subtypes Are Associated With Peculiar Gait Patterns in Parkinson's Disease.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Gait Analysis for Identifying Normal Cognition, Subjective Cognitive Decline, and Mild Cognitive Impairment in Parkinson Disease: Diagnostic Study.JMIR mHealth and uHealth · 2026Article
- Dual-task gait and gait-cognition coupling in patients with Parkinson's disease versus healthy older adults: moderation by cognitive status.Frontiers in aging neuroscience · 2026Article
- A Multi-sensor Gait Dataset Collected Under Non-standardized Dual-Task Conditions.Scientific data · 2025Article
- Dual-task-related gait patterns as possible marker of precocious and subclinical cognitive alterations in Parkinson disease.Scientific reports · 2025Article
- Biomechanics Parameters of Gait Analysis to Characterize Parkinson's Disease: A Scoping Review.Sensors (Basel, Switzerland) · 2025Article
- Observational
- Hot Topics and Frontiers of Resting-State fMRI in Parkinson's Disease: Research Trends and Paradigm Shifts From a Bibliometric Perspective.Parkinson's disease · 2025Review
- A kinematic dataset of locomotion with gait and sit-to-stand movements of young adults.Scientific data · 2024Article
- Impact of distinct cognitive domains on gait variability in individuals with mild cognitive impairment and dementia.Experimental brain research · 2024Article
- Enhanced Parkinson's gait, reduced fall risk, and improved cognitive function through multimodal rehabilitation combined with rivastigmine treatment.American journal of translational research · 2024Article
- Mild cognitive impairment in Parkinson's disease: current view.Frontiers in cognition · 2024Review
- Identification of a Gait Pattern for Detecting Mild Cognitive Impairment in Parkinson's Disease.Sensors (Basel, Switzerland) · 2023Article
- Interplay between gait and neuropsychiatric symptoms in Parkinson's Disease.European journal of translational myology · 2022Article
- Cognitive parameters can predict change of walking performance in advanced Parkinson's disease - Chances and limits of early rehabilitation.Frontiers in aging neuroscience · 2022Article
- Machine learning can predict mild cognitive impairment in Parkinson's disease.Frontiers in neurology · 2022Article
- Mild cognitive impairment in patients with Parkinson's disease: An updated mini-review and future outlook.Frontiers in aging neuroscience · 2022Review
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mild cognitive impairment (MCI) is frequent in Parkinson's disease (PD) and represents a risk factor for the development of dementia associated with PD (PDD). Since PDD has been associated with disability, caregiver burden, and an increase in health-related costs, early detection of MCI associated with PD (PD-MCI) and its biomarkers is crucial. Objective: Given that gait is considered a surrogate marker for cognitive decline in PD, the aim of this study was to compare gait patterns in PD-MCI subtypes in order to verify the existence of an association between specific gait features and particular MCI subtypes. Methods: A total of 67 patients with PD were consecutively enrolled and assessed by an extensive clinical and cognitive examination. Based on the neuropsychological examination, patients were diagnosed as patients with MCI (PD-MCI) and without MCI (no-PD-MCI) and categorized in MCI subtypes. All patients were evaluated using a motion capture system of a BTS Bioengineering equipped with six IR digital cameras. Gait of the patients was assessed in the ON-state under three different tasks (a single task and two dual tasks). Statistical analysis included the Results: Gait pattern was poorer in PD-MCI vs. no-PD-MCI in all tasks. Among PD-MCI subtypes, multiple-domain PD-MCI and amnestic PD-MCI were coupled with worse gait patterns, notably in the dual task. Conclusion: Both the magnitude of cognitive impairment and the presence of memory dysfunction are associated with increased measures of dynamic unbalance, especially in dual-task conditions, likely mirroring the progressive involvement of posterior cortical networks.
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