Evidence map›Paper›PMID 35299942›Full record

ArticleFrontiers in aging neuroscience2022

Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral Alterations and Cognitive Impairments and Insoluble Cortical Aβ42 Levels.

Sarah Holden, Payel Kundu, Eileen R S Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S Turker, Jacob Raber

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
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  6. Frontiers in aging neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sarah HoldenDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States.
Payel KunduDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States.
Eileen R S TorresDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States.
Reetesh SudhakarDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States.
Destine KrenikDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States.
Dmytro GrygoryevOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, United States.
Mitchel S TurkerOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, United States.
Jacob RaberDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States.
Oregon Health & Science University · USOregon State University · US

Funding

Neuroscience of Aging, Neurodegeneration and Alzheimer’s DiseaseT32AG055378 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI JACOB RABER, HENRYK F URBANSKI · 2018 to 2026
$4.3M
NIA NIH HHS T32 AG055378
6 · The paper itself

Abstract

Mice expressing human amyloid precursor protein (APP) containing the dominant Swedish and Iberian mutations (

Indexed as

amyloid precursor proteinapolipoprotein EAβ levelsbehavioral and cognitive performancegenetic interactions

Identifiers

PMID35299942
PMCPMC8922030
OpenAlexW4214873356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.