Evidence map›Paper›PMID 35299866›Full record

ArticleDisease markers2022

Correlation of Blood Biochemical Markers with Tardive Dyskinesia in Schizophrenic Patients.

Qian Wu, Fengjuan Yuan, Shuo Zhang, Weiting Liu, Qing Miao, Xinhua Zheng, Suxiang Lu, Kaijian Hou

Abstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Cortisol and cytokines in schizophrenia: A scoping review.Comprehensive psychoneuroendocrinology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian WuSchool of Medicine, Pingdingshan University, Pingdingshan City 467000, China.ORCID https://orcid.org/0000-0002-2049-6707
Fengjuan YuanSchool of Medicine, Pingdingshan University, Pingdingshan City 467000, China.ORCID https://orcid.org/0000-0001-7394-529X
Shuo ZhangDepartment of Endocrine and Metabolic Diseases, Longhu Hospital, The First Affiliated Hospital of Shantou University Medical College, Shantou City 515041, China.ORCID https://orcid.org/0000-0003-4040-8011
Weiting LiuSchool of Nursing, Anhui University of Chinese Medicine, Hefei City 230012, China.ORCID https://orcid.org/0000-0002-4234-9783
Qing MiaoDepartment of Physical Education, Henan University of Urban Construction, Pingdingshan City 467000, China.ORCID https://orcid.org/0000-0001-7075-4535
Xinhua ZhengSchool of Medicine, Pingdingshan University, Pingdingshan City 467000, China.ORCID https://orcid.org/0000-0002-1981-0519
Suxiang LuSchool of Medicine, Pingdingshan University, Pingdingshan City 467000, China.ORCID https://orcid.org/0000-0002-5946-1050
Kaijian HouDepartment of Endocrine and Metabolic Diseases, Longhu Hospital, The First Affiliated Hospital of Shantou University Medical College, Shantou City 515041, China.ORCID https://orcid.org/0000-0003-1733-0068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Oxidative stress factors and proinflammatory cytokines had been found to be involved in the pathogenesis of patients with tardive dyskinesia (TD). This study assumes that blood biochemical markers would have a link with TD in schizophrenia patients. To explore the correlation between blood biochemical markers and tardive dyskinesia in patients with schizophrenia (SCH). Methods: From January 2010 to August 2021, the inpatients who met the diagnostic criteria of schizophrenia in the Chinese Classification and Diagnosis Criteria of Mental Disorders (DSM-4) and the American Diagnostic and Statistical Manual of Mental Disorders (DSM-4) were followed up in the psychiatric outpatient department of Jinxia Street Community Health Service Center, Longhu District, Shantou City. The diagnostic criteria of Abnormal Involuntary Movement Scale (AIMS) used in the TD study of Schooler and Kane were used to screen the patients. Patients were divided into the schizophrenia (SCH group) and the schizophrenia with TD groups (TD group). Oxidative stress factors including Superoxide Dismutase1 (SOD1), Glutathione Peroxidase1 (GPX1), Malondialdehyde1 (MDA1), Catalase Activity1 (CAT1), and brain-derived neurotrophic factor 1 (BDNF1) and some inflammatory cytokines including interleukin-2 (IL-2), interleukin-6 (IL-6), interleukin-8 (IL-8), serum tumor necrosis factor (TNF- Results: Age and female were immutable risk factors for the development of TD, and there were significant differences in blood biochemical indices GPX1, MDA1, CAT1, and TNF- Conclusion: This study supports that oxidative stress and immune disorders are associated with TD patients. Blood biochemical markers GPX1, MDA1, CAT1, and TNF-

Indexed as

Age FactorsBiomarkersChinaFemaleHumansInterleukin-6MaleMiddle AgedOxidative StressSchizophreniaSex FactorsTardive DyskinesiaBiomarkersInterleukin-6

Identifiers

PMID35299866
PMCPMC8923804

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.