Evidence map›Paper›PMID 35299766›Full record

ArticleFrontiers in nutrition2022

Effects of

Wawaimuli Arozal, Emni Purwoningsih, Hee Jae Lee, Agian Jeffilano Barinda, Abdul Munim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. FermentedPharmaceutical biology · 2026
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  2. IBRO neuroscience reports · 2026
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  6. Water Extracts ofTheScientificWorldJournal · 2024
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  7. Frontiers in pharmacology · 2024
    Review
  8. Comparative Neuroprotective Effects ofTheScientificWorldJournal · 2024
    Article
  9. Article
  10. Journal of experimental pharmacology · 2023
    Article
  11. The Oil Formulation Derived fromJournal of experimental pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Wawaimuli ArozalDepartment of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Emni PurwoningsihDoctoral Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Hee Jae LeeDepartment of Pharmacology, School of Medicine, Kangwon National University, Chuncheon, South Korea.
Agian Jeffilano BarindaDepartment of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Abdul MunimDepartment of Pharmacognosy-Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
University of Indonesia · IDKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The cognitive deficit has frequently been found in the elderly population. Several studies have shown that every single part of Objective: We investigate whether Methods: In this study, 2 ml/kg body weight (BW) of MOO and 500 mg/kg BW of MOE were orally administered to the mice for 28 days, followed by intraperitoneal injection of Sco (1 mg/kg) at the day 22-28 to induce cognitive impairment in those mice. Results: The Sco group showed memory retention impairment represented by the Y-maze and novel object recognition tests, significant enhancement of acetylcholine esterase (AChE) activity in hippocampus tissue ( Conclusion: Our data reveal that MOO is preferable to MOE as a neuroprotective as evidenced by improving memory impairment. This effect, at least in part, through inhibiting the AChE and NF-κB activities and modulating the TrkB expression level.

Indexed as

acetylcholine esterase (AChE)formulationmemory impairmentMoringa oleiferanuclear factor kappa B (NF-κB)TrkB

Identifiers

PMID35299766
PMCPMC8922057
OpenAlexW4214519087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.