Evidence map›Paper›PMID 35299614›Full record

ArticleFrontiers in neurology2022

Relaxation-Compensated Chemical Exchange Saturation Transfer MRI in the Brain at 7T: Application in Relapsing-Remitting Multiple Sclerosis.

Kristin P O'Grady, Sanjana Satish, Quinn R Owen, Bailey A Box, Francesca Bagnato, Anna J E Combes, Sarah R Cook, Holly James Westervelt, Haley R Feiler, Richard D Lawless and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Kristin P O'GradyVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Sanjana SatishVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Quinn R OwenVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Bailey A BoxVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Francesca BagnatoNeuroimaging Unit, Division of Neuroimmunology, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States.
Anna J E CombesVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Sarah R CookVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Holly James WesterveltDivision of Behavioral and Cognitive Neurology, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States.
Haley R FeilerVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Richard D LawlessVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Asha SarmaDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Shekinah D MaloneSchool of Medicine, Meharry Medical College, Nashville, TN, United States.
Josephine M NdoloDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Keejin YoonNeuroimaging Unit, Division of Neuroimmunology, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, United States.
Richard D DortchDepartment of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, United States.
Baxter P RogersVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Seth A SmithVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States.
Vanderbilt University Medical Center · USVanderbilt University · USBarrow Neurological Institute · USMeharry Medical College · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
Structural and Functional MRI of the Cervical Spinal Cord in Multiple SclerosisR01NS109114 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SMITH, SETH A · 2018 to 2022
$1.7M
Development of Advanced MRI for the Thoracolumbar Spinal Cord for Clinical ApplicationK01EB030039 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI O'GRADY, KRISTIN POOLE · 2020 to 2023
$622k
Longitudinal Measurement of Neurodegeneration in two Murine Models of Multiple Sclerosis: A Clinical and Histopathologic Validation StudyR21NS116434 · NINDS · DARTMOUTH-HITCHCOCK CLINIC · PI BAGNATO, FRANCESCA ROSARIA, GILLI, FRANCESCA · 2021 to 2022
$431k
Glutamate-Sensitive, Quantitative MRI in MS: Application to Cognitive ImpairmentF32NS101788 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI O'GRADY, KRISTIN POOLE · 2017 to 2018
$86k
Improving the Assessment of Myelin and Axonal Integrity in Early Multiple SclerosisI01CX002160 · VA · VETERANS HEALTH ADMINISTRATION · PI BAGNATO, FRANCESCA ROSARIA · 2021 to 2025
–
CSRD VA I01 CX002160NCATS NIH HHS KL2 TR002245NCATS NIH HHS UL1 TR000445NIBIB NIH HHS K01 EB030039NINDS NIH HHS F32 NS101788NINDS NIH HHS R01 NS109114NINDS NIH HHS R21 NS116434
6 · The paper itself

Abstract

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) can probe tissue biochemistry

Indexed as

apparent exchange-dependent relaxation (AREX)chemical exchange saturation transfer (CEST)cognitionglutamatemetabolic imagingmultiple sclerosisultrahigh field

Identifiers

PMID35299614
PMCPMC8923037
OpenAlexW4214733351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.