ArticleActa paediatrica (Oslo, Norway : 1992)2022
Validation of central nervous system-induced seizures and other neurological variables in the Swedish Neonatal Quality Register.
Article in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Neurological Outcomes beyond Epilepsy following Electroencephalographically Verified Neonatal Seizures: A Swedish Nationwide Cohort Study.Neuroepidemiology · 2026Article
- Adverse long-term outcomes following seizures in non-asphyxiated term infants: A population-based cohort study.Pediatric research · 2026Article
- Grandmaternal Obesity and Risks of Birth Asphyxia-Related Complications in Grand-Offspring: A Countrywide Three-Generation Study.Obesity (Silver Spring, Md.) · 2025Article
- Improving UK data on avoidable perinatal brain injury: review of data dictionaries and consultation.Pediatric research · 2025Review
- Maternal Overweight and Obesity and Risk of Perinatal Ischemic Stroke: A Nationwide Cohort Study.Neurology · 2025Article
- Variation in electroencephalography and neuroimaging for children receiving extracorporeal membrane oxygenation.Critical care (London, England) · 2023Observational
- Low Apgar score and asphyxia complications at birth and risk of longer-term cardiovascular disease: a nationwide population-based study of term infants.The Lancet regional health. Europe · 2023Article
- Validation of central nervous system-induced seizures and other neurological variables in the Swedish Neonatal Quality Register.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
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4 authors.
Funding
Abstract
aimWe sought to validate neurological variables and relevant International Classification of Diseases, Tenth Revision (ICD-10) codes in the Swedish Neonatal Quality (SNQ) Register.
methodsRegister data were collected for 351 neonates, born between January 2009 and December 2016, who were treated at a neonatal unit in the Stockholm region on 385 occasions. They were eligible if the check-box for central nervous system (CNS)-induced seizures was ticked. The Register data, including relevant ICD-10 codes, were validated by checking the patients' electronic medical charts.
resultsMost of the neonates were born at term (76%) and weighed >2500 g (80%). The variable CNS-induced seizures had a positive predictive value of 46%. The ICD-10 diagnosis P90.9A had a positive predictive value of 90%. This comprises seizures validated with electroencephalography, amplitude-integrated electroencephalography or continuous function monitoring. The majority of the associated neurological variables in the Register had positive predictive values above 85%.
conclusionWhen the check-box was ticked for central nervous system-induced seizures, most of the neurological variables in the Register had high validity. However, the CNS-induced seizures variable per se had a lower positive predictive value. Future SNQ Register-based studies of such neonatal seizures should also include ICD-10 P90.9A.
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