Evidence map›Paper›PMID 35298707›Full record

ArticleWorld journal of microbiology & biotechnology2022

Characterization and mutagenesis of a novel Mycobacterium smegmatis-derived glutamate decarboxylase active at neutral pH.

Yudi Li, Guiying Chen, Fanglan Ge, Ting Dang, Yao Ren, Bei Zeng, Wei Li

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Cycloserine inhibits glutamate decarboxylase fromJournal of enzyme inhibition and medicinal chemistry · 2026
    Article
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  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yudi Li *College of life Sciences, Sichuan Normal University, 610068, Chengdu, China.
Guiying Chen *College of life Sciences, Sichuan Normal University, 610068, Chengdu, China.
Fanglan GeCollege of life Sciences, Sichuan Normal University, 610068, Chengdu, China.
Ting DangCollege of life Sciences, Sichuan Normal University, 610068, Chengdu, China.
Yao RenCollege of life Sciences, Sichuan Normal University, 610068, Chengdu, China.
Bei ZengCollege of life Sciences, Sichuan Normal University, 610068, Chengdu, China.
Wei LiCollege of life Sciences, Sichuan Normal University, 610068, Chengdu, China. liwei001@sicnu.edu.cn.ORCID http://orcid.org/0000-0001-5370-6072
Sichuan Normal University · CNSichuan University · CN

Funding

Department of Science and Technology of Sichuan Province 2018JY0310Sichuan provincial Science & Technology Department 2018JY0106
6 · The paper itself

Abstract

γ-aminobutyric acid (GABA) has various physiological functions and is widely used in medicine, food, and other fields. Glutamate decarboxylase (GAD) is a key enzyme that catalyzes the decarboxylation of L-glutamate to synthesize GABA. However, the industrial application of microorganism-derived GAD is limited by its rapid loss of enzymatic activity with pH approaching neutrality. In this study, a novel glutamate decarboxylase, GAD

Indexed as

Glutamate DecarboxylaseMycobacterium smegmatisHydrogen-Ion ConcentrationMolecular Docking SimulationMutagenesisGlutamate DecarboxylaseCharacterizationGlutamate decarboxylaseMutagenesisMycobacterium smegmatisNeutral pH

Identifiers

PMID35298707
OpenAlexW4220709536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.