Evidence map›Paper›PMID 35298652›Full record

ArticleJournal of animal science2022

Coated tannin supplementation improves growth performance, nutrients digestibility, and intestinal function in weaned piglets.

Tingting Xu, Xin Ma, Xinchen Zhou, Mengqi Qian, Zhiren Yang, Peiwen Cao, Xinyan Han

Open access · greenAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Tannic acid as a multi-target regulator of intestinal barrier function in livestock.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tingting XuThe Key Laboratory of Animal Nutrition and Feed Science in East China of Ministry of Agriculture, College of Animal Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Xin MaThe Key Laboratory of Animal Nutrition and Feed Science in East China of Ministry of Agriculture, College of Animal Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Xinchen ZhouHainan Institute of Zhejiang University, Yazhou Bay Science and Technology City, Zhejiang University, Sanya, Hainan 572025, China.
Mengqi QianThe Key Laboratory of Animal Nutrition and Feed Science in East China of Ministry of Agriculture, College of Animal Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Zhiren YangHainan Institute of Zhejiang University, Yazhou Bay Science and Technology City, Zhejiang University, Sanya, Hainan 572025, China.
Peiwen CaoThe Key Laboratory of Animal Nutrition and Feed Science in East China of Ministry of Agriculture, College of Animal Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Xinyan HanThe Key Laboratory of Animal Nutrition and Feed Science in East China of Ministry of Agriculture, College of Animal Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Zhejiang University · CNMinistry of Agriculture and Rural Affairs · CN

Funding

Research and Industrialization of Plant Tannin Synergistic Technology K18-517102-015
6 · The paper itself

Abstract

To explore the effect of coated tannin (CT) on the growth performance, nutrients digestibility, and intestinal function in weaned piglets, a total of 180 piglets Duroc × Landrace × Yorkshire (28 d old) weighing about 8.6 kg were randomly allotted to three treatments: 1) Con: basal diet (contains ZnSO4); 2) Tan: basal diet + 0.15% CT; and 3) ZnO: basal diet + ZnO (Zn content is 1,600 mg/kg). The results showed that 0.15% CT could highly increase the average daily gain and average daily feed intake of weaned piglets compared with the control group, especially decreasing diarrhea incidence significantly (P < 0.05). Compared with the control group, crude protein apparent digestibility and digestive enzyme activity of the piglets fed with 0.15% CT were enhanced obviously (P < 0.05). Meanwhile, the intestinal villi and microvilli arranged more densely, while the content of serum diamine oxidase was decreased, and the protein expressions of zonula occludens-1 (ZO-1) and claudin-1 were significantly upregulated (P < 0.05). In addition, CT altered the structure of intestinal microbiota and augmented some butyrate-producing bacteria such as Ruminococcaceae and Megasphaera. PICRUSt (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) analysis also showed that the abundances of pathways related to butyrate metabolism and tryptophan metabolism were increased; however, the function of lipopolysaccharide biosynthesis proteins was significantly decreased. The results demonstrated that 0.15% CT could improve growth performance, digestibility, and intestinal function of weaned piglets, and it had the potential to replace ZnO applied to farming.

Indexed as

TanninsZinc OxideAnimalsButyratesDietary SupplementsNutrientsPhylogenySwineButyratesNutrientsTanninsZinc Oxidecoated tannindigestibilitygrowth performanceintestinal functionweaned piglets

Identifiers

PMID35298652
PMCPMC9109020
OpenAlexW4220658148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.