Evidence map›Paper›PMID 35298500›Full record

ArticlePloS one2022

Seroepidemiology of SARS-CoV-2 in healthcare personnel working at the largest tertiary COVID-19 referral hospitals in Mexico City.

Vanessa Dávila-Conn, Maribel Soto-Nava, Yanink N Caro-Vega, Héctor E Paz-Juárez, Pedro García-Esparza, Daniela Tapia-Trejo, Marissa Pérez-García, Pablo F Belaunzarán-Zamudio, Gustavo Reyes-Terán, Juan G Sierra-Madero and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Vanessa Dávila-ConnCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.
Maribel Soto-NavaCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.
Yanink N Caro-VegaInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Héctor E Paz-JuárezCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.
Pedro García-EsparzaCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.
Daniela Tapia-TrejoCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.
Marissa Pérez-GarcíaCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.
Pablo F Belaunzarán-ZamudioIndependent investigator, Bethesda, MD, United States of America.
Gustavo Reyes-TeránInstitutos Nacionales de Salud y Hospitales de Alta Especialidad, Secretaría de Salud de México, Mexico City, Mexico.
Juan G Sierra-MaderoInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Arturo Galindo-FragaInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Santiago Ávila-RíosCentre for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico.ORCID 0000-0003-3371-4248
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXCambridge Information Group · USSecretaria de Salud · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe performed a longitudinal SARS-CoV-2 seroepidemiological study in healthcare personnel of the two largest tertiary COVID-19 referral hospitals in Mexico City.

methodsAll healthcare personnel, including staff physicians, physicians in training, nurses, laboratory technicians, researchers, students, housekeeping, maintenance, security, and administrative staff were invited to voluntarily participate, after written informed consent. Participants answered a computer-assisted self-administered interview and donated blood samples for antibody testing every three weeks from October 2020 to June 2021.

resultsA total of 883 participants (out of 3639 registered employees) contributed with at least one blood sample. The median age was 36 years (interquartile range: 28-46) and 70% were women. The most common occupations were nurse (28%), physician (24%), and administrative staff (22%). Two hundred and ninety participants (32.8%) had a positive-test result in any of the visits, yielding an overall adjusted prevalence of 33.5% for the whole study-period. Two hundred and thirty-five positive tests were identified at the baseline visit (prevalent cases), the remaining 55 positive tests were incident cases. Prevalent cases showed associations with both occupational (institution 2 vs. 1: adjusted odds ratio [aOR] = 2.24, 95% confidence interval [CI]: 1.54-3.25; laboratory technician vs. physician: aOR = 4.38, 95% CI: 1.75-10.93) and community (municipality of residence Xochimilco vs. Tlalpan: aOR = 2.03, 95% CI: 1.09-3.79) risk-factors. The incidence rate was 3.0 cases per 100 person-months. Incident cases were associated with community-acquired risk, due to contact with suspect/confirmed COVID-19 cases (HR = 2.45, 95% CI: 1.21-5.00).

conclusionsWe observed that between October 2020 and June 2021, healthcare workers of the two largest tertiary COVID-19 referral centers in Mexico City had similar level of exposure to SARS-CoV-2 than the general population. Most variables associated with exposure in this setting pointed toward community rather than occupational risk. Our observations are consistent with successful occupational medicine programs for SARS-CoV-2 infection control in the participating institutions but suggest the need to strengthen mitigation strategies in the community.

Indexed as

SARS-CoV-2AdultCOVID-19COVID-19 Serological TestingFemaleHumansMaleMexicoMiddle AgedPersonnel, HospitalRisk FactorsSeroepidemiologic StudiesTertiary Care Centers

Identifiers

PMID35298500
PMCPMC8929624
OpenAlexW4220777476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.