Evidence map›Paper›PMID 35298079›Full record

ArticleHepatology (Baltimore, Md.)2022

Improving the Model for End-Stage Liver Disease with sodium by incorporating kidney dysfunction types.

Giuseppe Cullaro, Elizabeth C Verna, Charles E McCulloch, Jennifer C Lai

Abstract read
In one paragraph

Article in Hepatology (Baltimore, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giuseppe CullaroDepartment of Medicine, University of California-San Francisco, San Francisco, California, USA.ORCID 0000-0002-2935-0245
Elizabeth C VernaCenter for Liver Disease and Transplantation, Columbia University, Vagelos College of Physicians and Surgeons, New York, New York, USA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.
Jennifer C LaiDepartment of Medicine, University of California-San Francisco, San Francisco, California, USA.ORCID 0000-0003-2092-6380

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI James P. Grenert · 1986 to 2026
$30.7M
The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationR01AG059183 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer C. Lai · 2018 to 2026
$9.9M
The Organoid and Cell Culture CoreP30DK132710 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Robert F. Schwabe · 2022 to 2026
$7.2M
Frailty and Functional Status in Older Liver Transplant PatientsK23AG048337 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAI, JENNIFER C. · 2014 to 2018
$911k
Application of Novel Biomarkers of Renal Health in Cirrhosis Patients to Stratify Risk of Acute Kidney Injury Occurrence and ReversibilityK23DK131278 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Giuseppe Cullaro · 2022 to 2026
$812k
NIA NIH HHS K23 AG048337NIA NIH HHS R01 AG059183NIDDK NIH HHS K23 DK131278NIDDK NIH HHS L30 DK133959NIDDK NIH HHS P30 DK026743NIDDK NIH HHS P30 DK132710
6 · The paper itself

Abstract

BACKGROUND AND

aimsWe investigated the impact of the inclusion of kidney dysfunction type on the discrimination and calibration of the Model for End-Stage Liver Disease with sodium (MELD-Na-KT) score. APPROACH AND

resultsWe included all adults listed for ≥90 days without exception points from January 1, 2008, through December 31, 2018. We defined kidney dysfunction types as follows: acute kidney disease (AKD; an increase of ≥0.3 mg/dL or ≥50% in serum creatinine in the last 7 days or fewer than 72 days of hemodialysis), chronic kidney disease (CKD; an estimated glomerular filtration rate <60 ml/min/1.73 m

conclusionsThis study demonstrates the feasibility and the potential for objectively defined kidney dysfunction types to enhance the prognostication of waitlist mortality provided by the MELD-Na score.

Indexed as

End Stage Liver DiseaseRenal Insufficiency, ChronicAdultHumansKidneyPrognosisRetrospective StudiesSeverity of Illness IndexSodiumWaiting ListsSodium

Identifiers

PMID35298079
PMCPMC9378344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.