Evidence map›Paper›PMID 35298036›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2022

Long-term cost-effectiveness of Dexcom G6 real-time continuous glucose monitoring system in people with type 1 diabetes in Australia.

J J Isitt, S Roze, D Tilden, N Arora, A J Palmer, T Jones, D Rentoul, P Lynch

Open access · hybridAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

J J IsittVyoo Agency, San Diego, California, USA.ORCID 0000-0003-1854-8798
S RozeVyoo Agency, Lyon, France.
D TildenTHEMA Consulting, Sydney, Australia.
N AroraTHEMA Consulting, Sydney, Australia.
A J PalmerMenzies Institute for Medical Research, The University of Tasmania, Hobart, Australia.ORCID 0000-0002-9703-7891
T JonesDepartment of Endocrinology and Diabetes, Perth Children's Hospital, Perth, Western Australia, Australia.ORCID 0000-0002-7989-1998
D RentoulDexcom, San Diego, California, USA.
P LynchDexcom, San Diego, California, USA.
Dexcom (United States) · USMelanoma Institute Australia · AUCentre international de recherche sur le cancer · FRHealth and Human Services Agency · USThe Kids Research Institute Australia · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionReal-time continuous glucose monitoring (rt-CGM) allows patients with diabetes to adjust insulin dosing, potentially improving glucose control. This study aimed to compare the long-term cost-effectiveness of the Dexcom G6 rt-CGM device versus self-monitoring of blood glucose (SMBG) and flash glucose monitoring (FGM) in Australia in people with type 1 diabetes (T1D).

methodsLong-term costs and clinical outcomes were estimated using the CORE Diabetes Model. Clinical input data for the analysis of rt-CGM versus SMBG and FGM were sourced from the DIAMOND study and a network meta-analysis, respectively. Rt-CGM and FGM were associated with quality of life (QoL) benefits due to reduced fear of hypoglycaemia (FoH) and fingerstick testing. Analyses were performed over a lifetime time horizon from an Australian healthcare payer perspective, including direct costs from published data. Future costs and clinical outcomes were discounted at 5% per annum.

resultsRt-CGM was associated with an increased quality-adjusted life expectancy of 1.199 quality-adjusted life years (QALYs), increased mean total lifetime costs of AUD 21,596 and an incremental cost-effectiveness ratio (ICER) of AUD 18,020 per QALY gained compared with SMBG. Compared with FGM, rt-CGM was associated with an increased quality-adjusted life expectancy of 0.569 QALYs, increased mean total lifetime costs of AUD 11,064 and an ICER of AUD 19,455 per QALY gained. Key drivers of outcomes included HbA

conclusionsDue to improved clinical outcomes and QoL gains rt-CGM is highly cost-effective compared with SMBG and FGM in people with T1D in Australia.

Indexed as

Diabetes Mellitus, Type 1HypoglycemiaAustraliaBlood GlucoseBlood Glucose Self-MonitoringCost-Benefit AnalysisHumansHypoglycemic AgentsNetwork Meta-Analysis as TopicQuality of LifeBlood GlucoseHypoglycemic AgentsAustraliacost-effectivenessreal-time continuous glucose monitoringrt-CGMtype 1 diabetes

Identifiers

PMID35298036
PMCPMC9310589
OpenAlexW4221039340

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.