ArticleCA: a cancer journal for clinicians2022
Female erectile tissues and sexual dysfunction after pelvic radiotherapy: A scoping review.
Article in CA: a cancer journal for clinicians, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Engineered dual-responsive mucoadhesive hydrogel co-delivering fullerenol against radiation-induced vaginal injury and microbiota dysbiosis.Materials today. Bio · 2026Article
- Oncosexology: A Narrative Review on Sexual Health and Quality of Life in Cancer Patients.Cancer medicine · 2026Review
- Sexual function in chronic illness and cancer perspectives of the patient, partner, and healthcare provider; innovations; and updates: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024).Sexual medicine reviews · 2026Review
- Magnetic Resonance Imaging Features as Predictors of Response and Prognosis Following Neoadjuvant Therapy in Rectal Cancer: A Retrospective Cohort Study.Clinical Medicine Insights. Oncology · 2026Article
- The "Undefined and Ignored Normal Tissue" Bulboclitoral Complex in Locally Advanced Cervical Cancer Treated with Definitive Radiochemotherapy: Is It Not the Organ at Risk?Medicina (Kaunas, Lithuania) · 2025Article
- Insomnia in Women Surviving Breast and Gynecological Cancers-A Narrative Review to Address the Hormonal Factor.Cancers · 2025Review
- A feasibility study of sexual organ-dose sparing volumetric modulated arc therapy in female low rectal cancer patients treated with three-dimensional conformal radiation therapy.Journal of applied clinical medical physics · 2025Article
- Breast and Pelvic Cancer Survivors' Preferences for Psychosexual Interventions to Address Sexual Health Concerns: A Qualitative Study.Psycho-oncology · 2025Article
- Sex-Based Bias in Artificial Intelligence-Based Segmentation Models in Clinical Oncology.Clinical oncology (Royal College of Radiologists (Great Britain)) · 2025Review
- Current advance of nanotechnology in diagnosis and treatment for malignant tumors.Signal transduction and targeted therapy · 2024Review
- Long-Term Patient-Reported Dyspareunia After Definitive Chemoradiation for Anal Cancer: Using the Anterior Vaginal Wall as an Organ-at-Risk to Define an Actionable Dosimetric Goal.Advances in radiation oncology · 2024Article
- Review
- Role of Nutraceuticals in Treating Erectile DysfunctionCurrent pharmaceutical biotechnology · 2024Review
- Cervical cancer treatment update: A Society of Gynecologic Oncology clinical practice statement.Gynecologic oncology · 2023Article
- Sexual health and treatment-related sexual dysfunction in sexual and gender minorities with prostate cancer.Nature reviews. Urology · 2023Review
- Predictors of female sexual problems in Shanxi, China: a population-based cross-sectional epidemiologic survey.Sexual medicine · 2023Article
- Incidence and predictors of toxicity in the management of vulvar squamous cell carcinoma treated with radiation therapy.Gynecologic oncology reports · 2022Article
- The mMolecular cancer · 2022Article
- A first radiotherapy application of functional bulboclitoris anatomy, a novel female sexual organ-at-risk, and organ-sparing feasibility study.The British journal of radiology · 2021Article
- Getting c-Literate: Bulboclitoris Functional Anatomy and Its Implications for Radiation Therapy.Practical radiation oncologyArticle
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
Sexual function is a vital aspect of human health and is recognized as a critical component of cancer survivorship. Understanding and evaluating the impacts of radiotherapy on female sexual function requires precise knowledge of the organs involved in sexual function and the relationship between radiotherapy exposure and sexual tissue function. Although substantial evidence exists describing the impact of radiotherapy on male erectile tissues and related clinical sexual outcomes, there is very little research in this area in females. The lack of biomedical data in female patients makes it difficult to design studies aimed at optimizing sexual function postradiotherapy for female pelvic malignancies. This scoping review identifies and categorizes current research on the impacts of radiotherapy on normal female erectile tissues, including damage to normal functioning, clinical outcomes of radiation-related female erectile tissue damage, and techniques to spare erectile tissues or therapies to treat such damage. An evaluation of the evidence was performed, and a summary of findings was generated according to Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) Extension for Scoping Reviews guidelines. Articles were included in the review that involved normal female erectile tissues and radiotherapy side effects. The results show that little scientific investigation into the impacts of radiotherapy on female erectile tissues has been performed. Collaborative scientific investigations by clinical, basic, and behavioral scientists in oncology and radiotherapy are needed to generate radiobiologic and clinical evidence to advance prospective evaluation, prevention, and mitigation strategies that may improve sexual outcomes in female patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.