Evidence map›Paper›PMID 35297658›Full record

ArticleMicrobiology spectrum2022

The Performance of Nine Commercial Serological Screening Assays for the Diagnosis of Lyme Borreliosis: a Multicenter Modified Two-Gate Design Study.

B J A Hoeve-Bakker, Mark Jonker, Afke H Brandenburg, P Martijn den Reijer, Foekje F Stelma, Alje P van Dam, Tamara van Gorkom, Karen Kerkhof, Steven F T Thijsen, Kristin Kremer

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Borrelia surface proteins: new horizons in Lyme disease diagnosis.Applied microbiology and biotechnology · 2025
    Review
  3. Evaluation of different standard and modified two-tier testing strategies for the laboratory diagnosis of lyme borreliosis in a European setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  4. High Prevalence of Borrelia burgdorferi Antibodies in Jaworzno, Poland: A Retrospective Study Revealing Endemic Lyme Borreliosis.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

B J A Hoeve-BakkerCentre for Infectious Disease Control, National Institute for Public Health and the Environmentgrid.31147.30 (RIVM), Bilthoven, the Netherlands.ORCID 0000-0002-3872-3437
Mark JonkerCentre for Infectious Disease Control, National Institute for Public Health and the Environmentgrid.31147.30 (RIVM), Bilthoven, the Netherlands.
Afke H BrandenburgIzore Centre for Infectious Diseases Friesland, Leeuwarden, the Netherlands.
P Martijn den ReijerDepartment of Medical Microbiology and Infection Prevention, Gelre Hospitalsgrid.415355.3 Apeldoorn, Apeldoorn, the Netherlands.
Foekje F StelmaRadboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
Alje P van DamDepartment of Medical Microbiology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Tamara van GorkomCentre for Infectious Disease Control, National Institute for Public Health and the Environmentgrid.31147.30 (RIVM), Bilthoven, the Netherlands.ORCID 0000-0002-1565-5902
Karen KerkhofCentre for Infectious Disease Control, National Institute for Public Health and the Environmentgrid.31147.30 (RIVM), Bilthoven, the Netherlands.
Steven F T ThijsenDepartment of Medical Microbiology and Immunology, Diakonessenhuis Hospital, Utrecht, the Netherlands.
Kristin KremerCentre for Infectious Disease Control, National Institute for Public Health and the Environmentgrid.31147.30 (RIVM), Bilthoven, the Netherlands.
National Institute for Public Health and the Environment · NLAmsterdam University Medical Centers · NLDiakonessenhuis hospital · NLGelre Hospitals · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this retrospective study, the performance of nine serological screening assays for Lyme borreliosis (LB) diagnostics was evaluated using a study population of LB cases and controls. Sera derived from 74 well-defined LB cases and 122 controls were included. The LB cases were diagnosed with erythema migrans (EM;

Indexed as

BorreliaLyme DiseaseAntibodies, BacterialHumansImmunoglobulin GImmunoglobulin MRetrospective StudiesAntibodies, BacterialImmunoglobulin GImmunoglobulin MBorreliaCLIAELISAevaluationIgGIgMLyme borreliosisLyme diseaseperformanceserology

Identifiers

PMID35297658
PMCPMC9045392
OpenAlexW4220697743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.