ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023
Daytime napping and Alzheimer's dementia: A potential bidirectional relationship.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
77 citing papers in PubMed, 4 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Sleep disorders increase the risk of dementia, Alzheimer's disease, and cognitive decline: a meta-analysis.GeroScience · 2025Pooled it
- Sleep characteristics and risk of Alzheimer's disease: a systematic review and meta-analysis of longitudinal studies.Journal of neurology · 2024Pooled it
- Pooled it
- Daytime naps and depression risk: A meta-analysis of observational studies.Frontiers in psychology · 2022Pooled it
- Intervention effects of telenursing based on M-O-A model in empty-nest older adult individuals with chronic diseases: a randomized controlled trial.Frontiers in public health · 2024Trial
- Wife-husband differences in the associations between sleep durations and global cognition among middle-aged and older married couples in China: a longitudinal dyadic analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Clinical features of sleep disturbance in temporal lobe variants of frontotemporal dementia.Journal of neurology · 2026Article
- Sleep fragmentation correlates with amyloid beta deposition at brain autopsy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Definition and Test-Retest Reliability of a Monitoring Method Integrating Accelerometric Actigraphy and Bluetooth Indoor Location Tracking Applied in a Long-Term Residential Unit for Persons With Dementia: Longitudinal Observational Study.JMIR mHealth and uHealth · 2026Observational
- Intermediate- and Long-Term Exposure to PMToxics · 2026Article
- Article
- Associations of sleep behaviors with white matter hyperintensity volume in middle-aged to older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Breaking the nap habit: one-year nap restriction mitigates memory decline in older adults.GeroScience · 2026Article
- Associations between sleep disturbance and cerebrospinal fluid Aβ, and shared proteomic signatures in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Objectively Measured Daytime Napping Patterns and All-Cause Mortality in Older Adults.JAMA network open · 2026Article
- Article
- Systematic Review on the Association Between Sleep and the Risk of Alzheimer's Disease: An Evolutionary Perspective.Evolutionary applications · 2026Review
- Article
- Individual Sleep Problems Are Associated With an Accelerated Decline in Multiple Cognitive Functions in Older Adults.Journal of sleep research · 2025Article
- Variability of longitudinal sleep monitoring in amyloid-negative and amyloid-positive cognitively unimpaired and mildly impaired older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
17 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
introductionDaytime napping is frequently seen in older adults. The longitudinal relationship between daytime napping and cognitive aging is unknown.
methodsUsing data from 1401 participants of the Rush Memory and Aging Project, we examined the longitudinal change of daytime napping inferred objectively by actigraphy, and the association with incident Alzheimer's dementia during up to 14-year follow-up.
resultsOlder adults tended to nap longer and more frequently with aging, while the progression of Alzheimer's dementia accelerates this change by more than doubling the annual increases in nap duration/frequency. Longer and more frequent daytime naps were associated with higher risk of Alzheimer's dementia. Interestingly, more excessive (longer or more frequent) daytime napping was correlated with worse cognition a year later, and conversely, worse cognition was correlated with more excessive naps a year later. DISCUSSION: Excessive daytime napping and Alzheimer's dementia may possess a bidirectional relationship or share common pathophysiological mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.