ArticleJournal of occupational health2022
Associations between chronic work stress and plasma chromogranin A/catestatin among healthy workers.
Article in Journal of occupational health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Plasma chromogranin a levels and their role in the etiology of anxiety disorders in children and adolescents.BMC psychiatry · 2026Article
- Comparison of Salivary Stress Biomarkers in Patients with and without Periodontal Diseases: A Cross-sectional Study.Oral health & preventive dentistry · 2026Article
- Effects of bright light therapy on cognition, sleep and psychological stress in older adults with mild-to-moderate cognitive impairment: a pilot study in long-term care facilities.BMC geriatrics · 2026Article
- Salivary and serum chromogranin A as biomarkers of acute stress during early fixed orthodontic treatment: a longitudinal study.Scientific reports · 2026Article
- Salivary cortisol, dehydroepiandrosterone, and chromogranin A levels in patients with gingivitis and periodontitis and a novel biomarker for psychological stress.Frontiers in endocrinology · 2023Article
- Role of Catestatin in the Cardiovascular System and Metabolic Disorders.Frontiers in cardiovascular medicine · 2022Review
- Associations between chronic work stress and plasma chromogranin A/catestatin among healthy workers.Journal of occupational health · 2022Article
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Authors and funding
6 authors.
Funding
Abstract
objectivesPlasma chromogranin A (CgA) may play a critical role on linking work stress to health outcomes. The aim of our study was to investigate the associations between work stress and plasma CgA levels in healthy workers without chronic diseases.
methodsThe study included 260 healthy workers from EHOP study. Work stressors were assessed by the Chinese version of the 23-item ERI-Q questionnaire. Plasma CgA and catestatin levels were measured by ELISA kits. The demographic characteristics were collected from medical records.
resultsAmong the final 260 subjects including 173 males (66.5%) and 87 females (33.5%), the average age was 37.6 ± 10.6 years old. Effort, overcommitment, and ERI were positively associated with plasma CgA level, respectively (r = 0.267, 0.319, and 0.304, all p < .001), while reward was negatively associated with CgA level (r = -0.237, p < .001). The workers with high effort, overcommitment, or ERI had significantly higher plasma CgA levels, while the workers with high rewards had significantly lower plasma CgA levels. The workers with both high overcommitment and high ERI had highest plasma CgA levels. In the linear regression analysis, after adjustment for confounders, effort, overcommitment, and ERI were respectively positively related to plasma CgA, while reward negatively related to plasma CgA. The associations between work stress and plasma catestatin was not significant. The ratio of CgA and catestatin was associated with work stress.
conclusionsWork stress is associated with plasma CgA which may be play a crucial role on the pathway from chronic work stress to cardiovascular diseases.
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