Evidence map›Paper›PMID 35297243›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2022

Eltrombopag for Treatment of Thrombocytopenia Following Hematopoietic Stem Cell Transplantation

Zeynep Tuğba Güven, Serhat Çelik, Bülent Eser, Mustafa Çetin, Ali Ünal, Leylagül Kaynar

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zeynep Tuğba GüvenErciyes University Faculty of Medicine, Department of Hematology, Kayseri, TurkeyORCID 0000-0003-1600-9731
Serhat ÇelikErciyes University Faculty of Medicine, Department of Hematology, Kayseri, Turkey
Bülent EserMedical Park Hospital, Antalya, TurkeyORCID 0000-0002-4513-3486
Mustafa ÇetinErciyes University Faculty of Medicine, Department of Hematology, Kayseri, Turkey
Ali ÜnalErciyes University Faculty of Medicine, Department of Hematology, Kayseri, Turkey
Leylagül KaynarErciyes University Faculty of Medicine, Department of Hematology, Kayseri, TurkeyORCID 0000-0002-2035-9462
Erciyes University · TRKayseri Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to evaluate the efficacy and safety of eltrombopag (ELT) in the treatment of thrombocytopenia following hematopoietic stem cell transplantation (HSCT). Materials and Methods: Forty-eight patients treated with ELT for thrombocytopenia after allogeneic or autologous transplantation at the Erciyes University Bone Marrow Transplantation Center between July 2017 and July 2021 were evaluated retrospectively. Results: Forty-eight HSCT recipients were included in this study. Thirty (62.5%) patients were evaluated as having experienced delayed platelet recovery (DPR) and 18 (37.5%) patients as having experienced secondary failure of platelet recovery (SFPR). The median platelet count before ELT treatment was 13x10 Conclusion: This real-life experience demonstrates that ELT is an effective and safe treatment option for thrombocytopenia after HSCT. The adequacy of bone marrow megakaryocytes before ELT treatment was an important factor affecting response to treatment.

Indexed as

Hematopoietic Stem Cell TransplantationThrombocytopeniaBenzoatesHumansHydrazinesPyrazolesRetrospective StudiesBenzoateseltrombopagHydrazinesPyrazolesEltrombopagHematopoietic stem celltransplantationPlatelet recoveryThrombocytopenia

Identifiers

PMID35297243
PMCPMC9160700
OpenAlexW4221072899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.