Evidence map›Paper›PMID 35297189›Full record

ArticleClinical and translational medicine2022

Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer.

Yinghui Zhu, Xin He, Shu Li, Yichao Gan, Zheng Li, Hanying Wang, Haojie Dong, Lei Zhang, Sheng-Li Xue, Yang Xu and 1 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yinghui ZhuDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
Xin HeDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
Shu LiDepartment of Hematology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yichao GanInstitute of Genetics, Zhejiang University, Hangzhou, China.
Zheng LiDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
Hanying WangDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
Haojie DongDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
Lei ZhangDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.
Sheng-Li XueDepartment of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China.
Yang XuDepartment of Hematology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ling LiDepartment of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA.ORCID 0000-0001-7568-939X

Funding

Targeting protein acetylation as a therapeutic approach for MDSR01HL141336 · NHLBI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI LI, LING · 2018 to 2022
$2.2M
Role of Protein Arginine Methyltransferase 9 in Acute Myeloid Leukemia MaintenanceR01CA248149 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI LI, LING · 2020 to 2024
$2.1M
Gusu Key Medical Talent Program, GSW2019007Jiangsu Province "333" project, a Social Development Project of the Science and Technology Department of Jiangsu, BE2021649National Natural Science Foundation of China 81572920National Natural Science Foundation of China 81970138Natural Science Foundation of Zhejiang Province of China, LY21H080005NCI NIH HHS R01 CA248149NHLBI NIH HHS R01 HL141336Translational Research Grant of NCRCH, 2020ZTranslational Research Grant of NCRCH, KMB05
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HMGA1a ProteinLeukemia, Myeloid, AcuteDrug Resistance, NeoplasmHumansPhosphorylationPhosphotransferasesHMGA1a ProteinPhosphotransferases

Identifiers

PMID35297189
PMCPMC8926901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.