Evidence map›Paper›PMID 35297102›Full record

ArticleJournal of clinical laboratory analysis2022

Prognostic value of albumin-related ratios in HBV-associated decompensated cirrhosis.

Tan Zhang, Bin Ye, JianJiang Shen

Abstract read
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Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  13. Comprehensive comparison of the prognostic value of systemic inflammation biomarkers for cancer cachexia: a multicenter prospective study.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Tan ZhangDepartment of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.
Bin YeDepartment of Critical Care Medicine, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.
JianJiang ShenDepartment of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.ORCID https://orcid.org/0000-0001-9202-826X

Funding

Health Department of Zhejiang Province 2019KY735
6 · The paper itself

Abstract

backgroundIdentification of effective and accurate prognostic biomarkers for hepatitis B virus-associated decompensated cirrhosis (HBV-DeCi) is challenging. This study was designed to determine and compare the prognostic value of albumin-related ratios (blood urea nitrogen-to-albumin ratio [BAR], C-reactive protein-to-albumin ratio [CAR], prothrombin time-international normalized ratio-to-albumin ratio [PTAR], neutrophil count-to-albumin ratio [NAR], and D-dimer-to-albumin ratio [DAR]) in HBV-DeCi patients.

methodsWe retrospectively recruited 161 HBV-DeCi patients. Receiver operating characteristic curve, DeLong test, and Cox regression analyses were used to estimate and compare the predictive value of these five albumin-related ratios and Model for End-Stage Liver Disease (MELD) score.

resultsA total of 29 (18.0%) patients had died 30 days after admission. The prognostic roles of CAR, DAR, PTAR, NAR, and BAR in HBV-DeCi were different. CAR, PTAR, NAR, and BAR were significantly higher in non-survivors compared with survivors. However, DAR did not differ between the two groups. The predictive power of BAR was superior to that of the other four albumin-related biomarkers and similar to that of MELD score. On multivariate analysis, BAR and MELD score were identified as independent prognostic factors, and the combination of BAR and MELD score may improve the prognostic accuracy in HBV-DeCi.

conclusionThe present findings suggest that BAR may be a simple and useful prognostic tool to predict mortality in HBV-DeCi patients.

Indexed as

End Stage Liver DiseaseHepatitis B virusAlbuminsBiomarkersHumansLiver CirrhosisPrognosisRetrospective StudiesROC CurveSeverity of Illness IndexAlbuminsBiomarkersalbumin-related ratiosdecompensated cirrhosishepatitis B virusprognosis

Identifiers

PMID35297102
PMCPMC8993660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.