Evidence map›Paper›PMID 35296968›Full record

SynthesisObesity surgery2022

Efficacy and Safety of Pharmacoprophylaxis for Venous Thromboembolism in Patients Undergoing Bariatric Surgery: a Systematic Review and Meta-analysis.

Ying Zhao, Zhikang Ye, Jianrui Lin, Zhiqi Zhang, Peirong Tian, Zhongtao Zhang, Peng Zhang, Xiangli Cui

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Association of venous thromboembolism prophylaxis with postoperative bleeding in bariatric surgery: an observational study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ying ZhaoDepartment of Pharmacy, Beijing Friendship Hospital, Capital Medical University, No.95 Yong-an Road, Xi-Cheng District, Beijing, 100050, China.
Zhikang YeDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, L8S2H6, Canada.
Jianrui LinDepartment of Pharmacy, Beijing Friendship Hospital, Capital Medical University, No.95 Yong-an Road, Xi-Cheng District, Beijing, 100050, China.
Zhiqi ZhangDepartment of Pharmacy, Beijing Friendship Hospital, Capital Medical University, No.95 Yong-an Road, Xi-Cheng District, Beijing, 100050, China.
Peirong TianDivision of Metabolic and Bariatric Surgery, General Surgery Center, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Zhongtao ZhangDivision of Metabolic and Bariatric Surgery, General Surgery Center, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. zhangzht@ccmu.edu.cn.
Peng ZhangDivision of Metabolic and Bariatric Surgery, General Surgery Center, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. zhangpg@yahoo.com.
Xiangli CuiDepartment of Pharmacy, Beijing Friendship Hospital, Capital Medical University, No.95 Yong-an Road, Xi-Cheng District, Beijing, 100050, China. xianglicui@ccmu.edu.cn.ORCID http://orcid.org/0000-0002-2992-5205
Capital Medical University · CNImpact · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to assess the efficacy and safety of pharmacoprophylaxis regimens for venous thromboembolism (VTE) in patients undergoing bariatric surgery. A total of 15 studies were included. Low molecular-weight heparins (LMWH) and fondaparinux may be equally effective in reducing VTE risk (OR 1.02, 95% confidence interval [CI] 0.14-7.39). Pooled estimate suggested uncertain effects of augmented LMWH dosing on VTE prophylaxis compared with standard dosing (OR 0.57, 95% CI 0.07-4.39), but may increase major bleeding (OR 3.03, 95% CI 0.38-23.96). Very low-quality evidence showed an inconclusive effect of extended prophylaxis on VTE (OR 0.54, 95% CI 0.15-1.90) and major bleeding (OR 1.24, 95% CI 0.92-1.68) compared with restricted prophylaxis. Standard LMWH dosing may be effective and safe. Current evidences are insufficient to support extended prophylaxis.

Indexed as

Bariatric SurgeryObesity, MorbidVenous ThromboembolismAnticoagulantsHemorrhageHeparin, Low-Molecular-WeightHumansAnticoagulantsHeparin, Low-Molecular-WeightBariatric surgeryDeep vein thrombosisMeta-analysisPharmacological prophylaxisPulmonary embolismVenous thromboembolism

Identifiers

PMID35296968
OpenAlexW4221029460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.