Evidence map›Paper›PMID 35296953›Full record

ArticleJournal of assisted reproduction and genetics2022

Is seminal quality worsening? A 20-year experience in Córdoba, Argentina.

Nicolás David Ramírez, Andrea Tissera, Rosa Molina, Pablo Gaggino, Arnaldo Mangeaud, Ana Carolina Martini

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nicolás David RamírezCátedra de Fisiología Humana, Instituto de Fisiología, Facultad de Ciencias Médicas (FCM), Universidad Nacional de Córdoba and Instituto de Investigaciones en Ciencias de la Salud (INICSA), Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET)-FCM, Santa Rosa 1085, X5000ESU, Córdoba, Argentina.ORCID http://orcid.org/0000-0001-9762-5637
Andrea TisseraLaboratorio de Andrología y Reproducción (LAR), Chacabuco 1089, X5000IIK, Córdoba, Argentina.
Rosa MolinaLaboratorio de Andrología y Reproducción (LAR), Chacabuco 1089, X5000IIK, Córdoba, Argentina.
Pablo GagginoLaboratorio de Andrología y Reproducción (LAR), Chacabuco 1089, X5000IIK, Córdoba, Argentina.
Arnaldo MangeaudCátedra de Bioestadística, Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Vélez Sarsfield 299, 5000, Córdoba, Argentina.ORCID http://orcid.org/0000-0002-7370-7256
Ana Carolina MartiniCátedra de Fisiología Humana, Instituto de Fisiología, Facultad de Ciencias Médicas (FCM), Universidad Nacional de Córdoba and Instituto de Investigaciones en Ciencias de la Salud (INICSA), Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET)-FCM, Santa Rosa 1085, X5000ESU, Córdoba, Argentina. acmartini2000@fcm.unc.edu.ar.ORCID http://orcid.org/0000-0003-3063-5640
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Nacional de Córdoba · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the possible variations in semen quality during the last 20 years in Córdoba, Argentina, and to identify possible causal lifestyle or genitourinary factors.

methodsRetrospective study of 23,130 patients attending an andrology laboratory. The 20-year period (2001-2020) was divided into four quinquenniums. Seminal parameters (sperm concentration, motility, morphology, viability, and membrane functional integrity) were classified as normal or abnormal according to WHO, and results were expressed as percentage of patients abnormal for each parameter per quinquennium. In addition, the percentage of patients per quinquennium exposed to the different risk factors (daily alcohol and/or tobacco consumption; occupational exposure to heat or toxics; history of parotitis or varicocele; and high body mass index, BMI) was reported.

resultsPatients included in our study did not show impairment in seminal quality over time. Beyond a transient decrease in normozoospermia in the second and third quinquennium, possibly explained by a parallel increase in teratozoospermia, other important parameters of the spermogram did not change. In fact, abnormalities in sperm concentration (oligozoospermia), total sperm count, viability and response to hypoosmotic test showed a decreasing trend over time. On the other hand, parotitis, varicocele, morbid obesity and regular exposition to heat/toxics were the factors more frequently associated with semen abnormalities; the last two increased their frequency over the study period.

conclusionThe population included in this study did not show a clear impairment in semen quality during the last 20 years. The decreasing patterns found were associated with high BMI and exposure to heat/toxics.

Indexed as

Infertility, MaleParotitisVaricoceleArgentinaHumansMaleRetrospective StudiesSemenSemen AnalysisSpermatozoaSperm CountSperm MotilityAlcoholHeat/toxicsObesitySeminal qualitySmoking

Identifiers

PMID35296953
PMCPMC9107558
OpenAlexW4220668168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.