SynthesisEuropean journal of applied physiology2022
The effect of exercise on left ventricular global longitudinal strain.
Synthesis in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of High-intensity Interval Training on Myocardial Strain in Patients With Metabolic Syndrome
Effect of Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction
Who cites it
20 citing papers in PubMed.
- Exercise-induced changes in left ventricular strain are affected by interleukin-6 activity: An exploratory analysis of a randomised-controlled trial in humans with abdominal obesity.Experimental physiology · 2024Trial
- Influence of Physical Training after a Myocardial Infarction on Left Ventricular Contraction Mechanics.Arquivos brasileiros de cardiologia · 2023Trial
- Predictive Effect of Echocardiographic Assessment of Myocardial Efficiency on Martial Arts Performance.Journal of sports science & medicine · 2026Observational
- Effects of combined training on heart rate variability and cardiac function and structure in individuals with grade 1 obesity.Physiological reports · 2026Article
- Influence of Endurance Training, High-Intensity Interval Training, and Acute Exercise on Left Ventricular Mechanics: A Systematic Review.Journal of clinical medicine · 2025Review
- High-Intensity Interval Training and Moderate-Intensity Continuous Training on Ventricular-Arterial Coupling (VAC) in Young Women With Obesity.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- A pilot exercise intervention to evaluate the role of cardiorespiratory fitness in modulating cardiotoxicity among childhood cancer survivors exposed to anthracycline therapy.Cardio-oncology (London, England) · 2025Article
- Higher Physical Activity Is Associated with Improved Ventricular-Arterial Coupling: Assessment Using the cfPWV/GLS Ratio in Primary Care-A Pilot Study.Journal of cardiovascular development and disease · 2025Article
- Diastolic global longitudinal strain and acute ischemic stroke: a hidden relationship?BMC cardiovascular disorders · 2025Article
- Impact of High Intensity Contact Physical Activity During a Match on Echocardiographic Parameters and High-Sensitivity Troponin I in Competitive Rugby Players.Journal of clinical medicine · 2025Article
- Longitudinal Displacement for Left Ventricular Function Assessment.Journal of cardiovascular development and disease · 2025Article
- Critical Appraisal of Pharmaceutical Therapy in Diabetic Cardiomyopathy-Challenges and Prospectives.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Article
- Ultrasound speckle tracking imaging measurement of endocardial longitudinal strain for evaluation of prognostic value of "new quadruple" therapy in patients with chronic heart failure.Frontiers in endocrinology · 2025Article
- Comparing the Effect of Moderate-Intensity Versus High-Intensity Interval Training Exercise on Global Longitudinal Strain (GLS) in Cardiovascular Patients: Systematic Review and Meta-Analysis.Cardiology research and practice · 2025Review
- The Clinical Outcome of Cardiac Rehabilitation in Coronary Artery Disease Patients with Regard to the Presence of Left Ventricular Systolic Dysfunction.Journal of clinical medicine · 2024Article
- Physical exercise and cardiovascular response: design and implementation of a pediatric CMR cohort study.The international journal of cardiovascular imaging · 2023Article
- Left Ventricular Mechanics: Untwisting the Pathways of the Cardiovascular Response to Exercise.Arquivos brasileiros de cardiologia · 2023Article
- Benefits in Cardiac Function from a Remote Exercise Program in Children with Obesity.International journal of environmental research and public health · 2023Article
- Exercise training affects hemodynamics and exercise capacity in cases of heart failure with preserved ejection fraction: a non-randomized controlled trial in individuals aged 65-80 years.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise improves measures of cardiovascular (CV) health and function. But as traditional measures improve gradually, it can be difficult to identify the effectiveness of an exercise intervention in the short-term. Left ventricular global longitudinal strain (LVGLS) is a highly sensitive CV imaging measure that detects signs of myocardial dysfunction prior to more traditional measures, with reductions in LVGLS a strong prognostic indicator of future CV dysfunction and mortality. Due to its sensitivity, LVGLS may offer useful method of tracking the effectiveness of an exercise intervention on CV function in the short-term, providing practitioners useful information to improve patient care in exercise settings. However, the effect of exercise on LVGLS is unclear. This systematic review and meta-analysis aimed to determine the effect exercise has on LVGLS across a range of populations. Included studies assessed LVGLS pre-post an exercise intervention (minimum 2 weeks) in adults 18 years and over, and were published in English from 2000 onwards. Study-level random-effects meta-analyses were performed using Stata (v16.1) to calculate summary standardized mean differences (SMD) and 95% confidence intervals (CI). 39 studies met selection criteria, with 35 included in meta-analyses (1765 participants). In primary analyses, a significant improvement in LVGLS was observed in populations with CV disease (SMD = 0.59; 95% CI 0.16-1.02; p = 0.01), however, no significant effect of exercise was observed in CV risk factor and healthy populations. In populations with CV disease, LVGLS could be used as an early biomarker to determine the effectiveness of an exercise regime before changes in other clinical measures are observed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.