ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022
The Development of Receptive Field Tuning Properties in Mouse Binocular Primary Visual Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 31 citations in OpenAlex.
- Eye-specific drive and binocular suppression in mouse visual cortex during critical period development.bioRxiv : the preprint server for biology · 2026Article
- Mismatch negativity matures in adolescence and without sensitivity to microglial depletion.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- PSD-95 drives binocular vision maturation critical for predation.bioRxiv : the preprint server for biology · 2026Article
- Mouse predation is dependent on a population of POU6F2-positive retinal ganglion cells.iScience · 2026Article
- A mouse model for cerebral/cortical visual impairment (CVI) impairs vision and disrupts the spatial frequency tuning of neurons in visual cortex.Experimental neurology · 2026Article
- Binocular Circuitry as a Model for Understanding Experience-Dependent Circuit Development across the Mammalian Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
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- Article
- The Richness of Vision in the Mammalian Brain: Neural Codes for Visual Perception and Behavior in Three Dimensions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Mismatch negativity develops in adolescence and independently of microglia.bioRxiv : the preprint server for biology · 2025Article
- A mouse model for cerebral/cortical visual impairment (CVI) impairs vision and disrupts the spatial frequency tuning of neurons in visual cortex.bioRxiv : the preprint server for biology · 2025Article
- Representational drift gates critical-period plasticity in mouse visual cortex.Current biology : CB · 2025Article
- A Critical Look at Critical Periods.Annual review of vision science · 2025Review
- Experience-dependent plasticity of multiple receptive field properties in lateral geniculate binocular neurons during the critical period.Frontiers in cellular neuroscience · 2025Article
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- Microglia are dispensable for experience-dependent refinement of mouse visual circuitry.Nature neuroscience · 2024Article
- Predicting Single Neuron Responses of the Primary Visual Cortex with Deep Learning Model.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Mammals Achieve Common Neural Coverage of Visual Scenes Using Distinct Sampling Behaviors.eNeuro · 2024Article
- Development of ocular dominance columns across rodents and other species: revisiting the concept of critical period plasticity.Frontiers in neural circuits · 2024Review
- Monocular deprivation during the critical period alters neuronal tuning and the composition of visual circuitry.PLoS biology · 2023Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
The mouse primary visual cortex is a model system for understanding the relationship between cortical structure, function, and behavior (Seabrook et al., 2017; Chaplin and Margrie, 2020; Hooks and Chen, 2020; Saleem, 2020; Flossmann and Rochefort, 2021). Binocular neurons in V1 are the cellular basis of binocular vision, which is required for predation (Scholl et al., 2013; Hoy et al., 2016; La Chioma et al., 2020; Berson, 2021; Johnson et al., 2021). The normal development of binocular responses, however, has not been systematically measured. Here, we measure tuning properties of neurons to either eye in awake mice of either sex from eye opening to the closure of the critical period. At eye opening, we find an adult-like fraction of neurons responding to the contralateral-eye stimulation, which are selective for orientation and spatial frequency; few neurons respond to ipsilateral eye, and their tuning is immature. Fraction of ipsilateral-eye responses increases rapidly in the first few days after eye opening and more slowly thereafter, reaching adult levels by critical period closure. Tuning of these responses improves with a similar time course. The development and tuning of binocular responses parallel that of ipsilateral-eye responses. Four days after eye opening, monocular neurons respond to a full range of orientations but become more biased to cardinal orientations. Binocular responses, by contrast, lose their cardinal bias with age. Together, these data provide an in-depth accounting of the development of monocular and binocular responses in the binocular region of mouse V1 using a consistent set of visual stimuli and measurements.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.