Observational studyBMJ open2022
Prevalence and associated factors of frailty among Southern Chinese Han patients on haemodialysis: a multicentre, observational cross-sectional study.
Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Frailty in maintenance hemodialysis: a systematic review and meta-analysis of prevalence and risk factors.International urology and nephrology · 2026Pooled it
- The prevalence of frailty among older adults with maintenance hemodialysis: a systematic.BMC nephrology · 2025Pooled it
- Global prevalence of frailty in hemodialysis patients: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- The effect of recreational therapy application on depression in hemodialysis patients: a randomized clinical trial.International urology and nephrology · 2025Trial
- A Tilburg Frailty Indicator (TFI)-based frailty classification model for older maintenance hemodialysis patients: a cross-sectional study.BMC geriatrics · 2026Article
- Comparison of diagnostic characteristics of four frailty screening tools in maintenance hemodialysis patients.International urology and nephrology · 2026Article
- Frailty in Focus: A Scoping Review of Frailty Instruments from the Kidney Disease Aging Research Collaborative.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Analysis of frailty status and its influencing factors in maintenance hemodialysis patients based on the health ecological model.BMC nephrology · 2025Article
- The relationship between disability, anxiety and depression in older adults with chronic disease comorbidities: the mediating role of frailty.BMC geriatrics · 2025Article
- Prevalence and correlates of anxiety and depression among chronically ill older adults in Zunyi, China: a cross-sectional study.Frontiers in psychology · 2025Article
- The Interplay of Anxiety, Depression, Sleep Quality, and Socioeconomic Factors in Somali Hemodialysis Patients.Brain sciences · 2024Article
- Depression Among Hemodialysis Patients: Related Factors and the Impact of Insomnia and Fatigue.Cureus · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesFrailty has been extensively studied in the general population. However, there is little information on frailty among patients undergoing haemodialysis (HD) in China. This study analysed the prevalence and associated factors of frailty among Southern Chinese Han patients on HD.
designObservational cross-sectional study.
settingThree HD centres in Southern China.
participantsThree hundred patients who underwent regular HD between June 2019 and October 2019. MAIN OUTCOMES AND MEASURES: Frailty was assessed using the Tilburg indicator of frailty (TFI) questionnaire, and the psychological status of the respondents was evaluated by the Self-Rating Depression Scale (SDS) and the Self-Rating Anxiety Scale (SAS).
resultsSeventy-five per cent of participants were in the frailty group, and the TFI score of HD patients was 6.89±2.87, with 8.15±2.06 in the frailty group and 2.87±1.31 in the non-frailty group. Frailty patients had higher SDS and SAS scores, and were more likely to suffer depression and anxiety than non-frailty patients. Multivariate logistic regression analysis excluding depression and anxiety showed that age, Charlson Comorbidity Index (excluding end-stage renal disease), a nuclear family (compared with living alone), and albumin were independently associated with frailty (all p<0.05). In the model including depression and anxiety, age, diabetes mellitus, living as a couple (compared with living alone), a nuclear family (compared with living alone), an extended family (compared with living alone), low phosphorus, depression and anxiety were associated with frailty by multivariate logistic regression analysis (all p<0.05).
conclusionsApproximately three-quarters of patients with HD in Southern China are frail, often accompanied with depression and anxiety. Age, diabetes mellitus, family structure, phosphorus, depression and anxiety were associated with frailty.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.