Evidence map›Paper›PMID 35296472›Full record

ArticleBMJ open2022

Dose-response relationship between body mass index and tuberculosis in China: a population-based cohort study.

Jinou Chen, Shun Zha, Jinglong Hou, Kunyun Lu, Yubing Qiu, Rui Yang, Ling Li, Yunbin Yang, Lin Xu

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Undernutrition as a risk factor for tuberculosis disease.The Cochrane database of systematic reviews · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jinou ChenDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.ORCID 0000-0001-6074-2178
Shun ZhaDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Jinglong HouDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Kunyun LuDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Yubing QiuDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Rui YangDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Ling LiDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Yunbin YangDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Lin XuDivision of Tuberculosis Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China xulinth@hotmail.com.ORCID 0000-0003-4512-347X
Yunnan Center for Disease Control And Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to describe and quantify the relationship between body mass index (BMI) and tuberculosis (TB) incidence.

designA population-based prospective cohort study.

settingTen randomly selected communities in the southwestern mountainous region of China.

participantsParticipants who had resided in study sites before screening for at least 6 months were eligible. Those who refused to participate or were temporary residents (who resided less than 6 months during three waves of screening) were excluded. The present research included 26 022 participants aged over 15 years for analyses.

interventionsThe cohort study conducted three rounds of TB screening from 2013 to 2015. Face-to-face surveys for participants were carried out. TB symptoms positivity suspects underwent chest X-ray and sputum smear test for diagnosis. PRIMARY OUTCOME MEASURES: The study outcome was the diagnosed active TB in the second and third rounds of screening.

resultsDuring the follow-up of 2.25 years, 43 cases developed TB in 44 574.4 person-years. The negative log-linear relationship between BMI and TB incidence was fitted (adjusted

conclusionsThe study provided evidence for a negative association between BMI and TB development in Chinese adults. It suggests the inverse dose-response relationship between BMI and TB incidence, and implies an optimal cut-off point of BMI for screening strategy.

Indexed as

TuberculosisAdultAgedBody Mass IndexChinaCohort StudiesFemaleHumansProspective Studiesepidemiologypublic healthtuberculosis

Identifiers

PMID35296472
PMCPMC8928331
OpenAlexW4221109067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.