Evidence map›Paper›PMID 35296460›Full record

ReviewBMJ global health2022

Situation of snakebite, antivenom market and access to antivenoms in ASEAN countries.

Chanthawat Patikorn, Ahmad Khaldun Ismail, Syafiq Asnawi Zainal Abidin, Francis Bonn Blanco, Jörg Blessmann, Khamla Choumlivong, John David Comandante, Uyen Vy Doan, Zainalabidin Mohamed Ismail, Yi Yi Khine and 11 more

Abstract readReview
In one paragraph

Review in BMJ global health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Chanthawat PatikornDepartment of Social and Administrative Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Ahmad Khaldun IsmailDepartment of Emergency Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Bandar Tun Razak, Kuala Lumpur, Malaysia.
Syafiq Asnawi Zainal AbidinJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.
Francis Bonn BlancoDepartment of Emergency Medicine, Ospital ng Muntinlupa, Muntinlupa City, Philippines.
Jörg BlessmannDepartment of Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Khamla ChoumlivongSetthathirath Hospital, Vientiane, Lao People's Democratic Republic.
John David ComandanteDepartment of Emergency, Prehospital, Disaster and Ambulatory Care Medicine, Ospital ng Makati, Makati City, Philippines.
Uyen Vy DoanDivision of Medical Toxicology, Cho Ray Hospital, Ho Chi Minh City, Viet Nam.
Zainalabidin Mohamed IsmailEmergency and Trauma Department, Hospital Tengku Ampuan Afzan, Kuantan, Pahang, Malaysia.
Yi Yi KhineNephrology Department, Thingangyun Sanpya General Hospital (TSGH), Yangon, Myanmar.
Tri MaharaniNational Institute of Research and Development, Ministry of Health Indonesia, Jakarta, Indonesia.
Myat Thet NweMyanmar Snakebite Project, Mandalay, Myanmar.
Reza Murad QamruddinEmergency and Trauma Department, Hospital Melaka, Melaka, Malaysia.
Ruth Sabrina SafferiEmergency and Trauma Department, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia.
Emelia SantamariaHealth Emergencies and Disasters (HEAD) Study Group, National Institutes of Health, University of the Philippines-Manila, Manila, Philippines.
Patrick Joseph G TiglaoDepartment of Emergency Medicine, Eastern Visayas Regional Medical Center, Tacloban City, Philippines.
Satariya TrakulsrichaiDepartment of Emergency Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Taksa VasaruchapongSnake Farm, Queen Saovabha Memorial Institute, The Thai Red Cross Society, Bangkok, Thailand.
Nathorn ChaiyakunaprukDepartment of Pharmacotherapy, The University of Utah College of Pharmacy, Salt Lake City, Utah, USA.
Suthira TaychakhoonavudhDepartment of Social and Administrative Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand suthira.t@chula.ac.th.
Iekhsan OthmanJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionSnakebite envenoming is a neglected tropical disease posing public health challenges globally. The Association of Southeast Asian Nations (ASEAN) countries are among the tropical regions with disproportionately high incidence of snakebite. Hence, this study aimed to review the situation of snakebite, antivenom market and access to antivenoms in ASEAN.

methodsThis mixed-methods study included comprehensive literature review and in-depth interviews with key informants to assess the situation of management system of snakebite, antivenom market and access to antivenoms in seven ASEAN countries, including Malaysia, Thailand, Indonesia, Philippines, Vietnam, Lao PDR and Myanmar. Data were analysed by a framework method.

resultsASEAN have developed various strategies to improve outcomes of snakebite victims. Five domestic antivenom manufacturers in the region produce up to 288 375 vials of antivenoms annually with the value of US$13 058 053 million which could treat 42 213 snakebite victims. However, there remain challenges to be addressed especially the lack of snakebite-related informatics system, inadequate antivenoms at the healthcare facilities and when the majority of snakebite victims seek traditional healers instead of conventional treatment.

conclusionImproving the situation of snakebite and antivenom is not only about the availability of antivenom, but the whole landscape of surrounding management and supporting system. The assessment of the situation of snakebite and antivenom is crucial for countries or regions where snakebites are prevalent to recognise their current standpoint to inform the development of strategies to achieve the goal set by the WHO of halving the global burden of snakebite by 2030.

Indexed as

AntiveninsSnake BitesHumansNeglected DiseasesPhilippinesPublic HealthAntiveninsHealth systemsPublic HealthSnake bite, stings and other evenoming

Identifiers

PMID35296460
PMCPMC8928241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.