Evidence map›Paper›PMID 35296390›Full record

ArticleThe journal of pain2022

Confronting Racism in All Forms of Pain Research: Reframing Study Designs.

Janelle E Letzen, Vani A Mathur, Mary R Janevic, Michael D Burton, Anna M Hood, Calia A Morais, Staja Q Booker, Claudia M Campbell, Edwin N Aroke, Burel R Goodin and 2 more

Open access · greenAbstract read
In one paragraph

Article in The journal of pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
39.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Topical ophthalmic anesthetics for corneal abrasions.The Cochrane database of systematic reviews · 2023
    Pooled it
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  12. Chronic pain lived experience of pediatric sickle cell disease: A qualitative study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
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  14. Article
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  16. Article
  17. Assessing and Managing Pain in Dementias: Insights From Interdisciplinary Text Message Communications.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2025
    Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Janelle E LetzenDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: Jletzen1@jhmi.edu.
Vani A MathurDepartment of Psychological and Brain Sciences, Texas A&M University, College Station, Texas; Texas A&M Institute for Neuroscience, Texas A&M University, College Station, Texas.
Mary R JanevicDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan.
Michael D BurtonDepartment of Neuroscience, Neuroimmunology and Behavior Group, Center for Advanced Pain Studies (CAPS), University of Texas at Dallas, Richardson, Texas.
Anna M HoodManchester Centre for Health Psychology, Division of Psychology and Mental Health, University of Manchester, Manchester, UK.
Calia A MoraisDepartment of Medicine, Division of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Staja Q BookerPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, Florida; Department of Biobehavioral Nursing Science, College of Nursing, University of Florida, Gainesville, Florida.
Claudia M CampbellDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Edwin N ArokeSchool of Nursing, Nurse Anesthesia Program, Department of Acute, Chronic, & Continuing Care, University of Alabama at Birmingham, Birmingham, Alabama.
Burel R GoodinDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, Alabama.
Lisa C CampbellDepartment of Psychology, East Carolina University, Greenville, North Carolina.
Ericka N MerriwetherDepartment of Physical Therapy, Steinhardt School of Culture, Education, and Human Development, New York University, New York, New York; Department of Medicine, NYU Grossman School of Medicine, New York University, New York, New York.
University of Alabama at Birmingham · USJohns Hopkins University · USEast Carolina University · USMichigan Department of Health and Human Services · USNew York University · USTexas A&M University · USThe University of Texas at Dallas · USUniversity of Florida · USUniversity of Manchester · GB

Funding

Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
The Impact of Insomnia on Pain, Physical Function, and Inflammation in HIVR01HL147603 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOODIN, BUREL R., SORGE, ROBERT · 2019 to 2022
$2.8M
Racial and Socioeconomic Differences in Chronic Low Back PainR01MD010441 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOODIN, BUREL R., SORGE, ROBERT · 2017 to 2021
$2.6M
University of Florida Resource Center for Minority Aging ResearchP30AG059297 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2018 to 2022
$2.2M
Ethnic differences in endogenous pain regulation: PET imaging of opioid receptorsR01MD009063 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE · 2014 to 2018
$2.1M
Epigenomic and Gene Expression Signatures of Racial Differences in Chronic Low Back PainR01AR079178 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AROKE, EDWIN NGOMUEH · 2021 to 2024
$1.6M
The Role of Cell-specific TLR-4 Signaling in Developing Chronic PainK22NS096030 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI BURTON, MICHAEL D · 2016 to 2019
$838k
A low-intensity, cognitive-behavioral self-management intervention for chronic musculoskeletal pain in older adultsK01AG050706 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JANEVIC, MARY ROSE · 2016 to 2020
$580k
Investigating Movement-evoked Pain in osteoArthritic Conditions (IMPACT): An Observational Study to Inform Culturally-Tailored Intervention DevelopmentK23AR076463 · NIAMS · UNIVERSITY OF FLORIDA · PI BOOKER, STAJA · 2020 to 2022
$379k
Measuring the Impact of Racism-Induced Medical Mistrust on Placebo Analgesia.K23NS124935 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LETZEN, JANELLE E · 2021 to 2021
$191k
NHLBI NIH HHS R01 HL147603NIAMS NIH HHS K23 AR076463NIAMS NIH HHS R01 AR079178NIA NIH HHS K01 AG050706NIA NIH HHS L30 AG074196NIA NIH HHS P30 AG022845NIA NIH HHS P30 AG059297NIDDK NIH HHS P30 DK092926NIMHD NIH HHS R01 MD009063NIMHD NIH HHS R01 MD010441NINDS NIH HHS K22 NS096030NINDS NIH HHS K23 NS124935
6 · The paper itself

Abstract

This second paper in a 3-part series on antiracism in pain research across the translational spectrum focuses on study design factors. Although objectivity is a cornerstone value of science, subjectivity is embedded in every step of the research process as investigators make choices about who they collaborate with, which research questions they ask, how they recruit participants, which research tools they use, and how they analyze and interpret data. We present theory and evidence from disciplines such as sociology, medical anthropology, statistics, and public health to discuss 4 common study design factors, including 1) the dominant biomedical narrative of pain that restricts funding and exploration of social indicators of pain, 2) low diversity and inclusion in pain research enrollment that restricts generalizability to racialized groups, 3) the use of "race" or "ethnicity" as a statistical variable and proxy for lived experiences (eg, racism, resilience), and 4) limited modeling in preclinical research for the impact of social factors on pain physiology. The information presented in this article is intended to start conversations across stakeholders in the pain field to explore how we can come together to adopt antiracism practices in our work at large to achieve equity for racialized groups. PERSPECTIVE: This is the second paper in a 3-part series on antiracism in pain research. This part identifies common study design factors that risk hindering progress toward pain care equity. We suggest reframes using an antiracism framework for these factors to encourage all pain investigators to collectively make strides toward equity.

Indexed as

RacismEthnicityHumansPainPublic HealthResearch Designantiracismmethodspain care equitypain disparitiesRacism

Identifiers

PMID35296390
PMCPMC9472383
OpenAlexW4214617036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.