ArticleBMC geriatrics2022
Low muscle mass is an independent risk factor for postoperative blood transfusion in total knee arthroplasty: a retrospective, propensity score-matched cohort study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Impact of sarcopenia on clinical outcomes of older adults undergoing total knee arthroplasty for osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Research hotspots and trends of sarcopenia in orthopaedic surgery: a bibliometric analysis from 2003 to 2023.Frontiers in surgery · 2025Pooled it
- Low Skeletal Muscle Mass and the Incidence of Delirium in Hospitalized Older Patients: A Systematic Review and Meta-Analysis of Observational Studies.International journal of clinical practice · 2023Pooled it
- Sarcopenia and Postoperative Outcomes Following Total Knee Arthroplasty: A Systematic Review of Observational Studies.Journal of clinical medicine · 2026Review
- Predictors and Early Outcomes of Hidden Blood Loss Following Surgery for Spinal Metastases: A Retrospective Study Focusing on Tomita Type 1-5 Lesions.Journal of clinical medicine · 2026Article
- Novel fat infiltration combined with muscle parameters for predicting postoperative complications following total knee arthroplasty: a retrospective study.BMC musculoskeletal disorders · 2025Article
- CT-based sarcopenia is independently associated with blood transfusions after hip arthroplasty in elderly patients with femoral neck fractures: a retrospective cohort study.BMC geriatrics · 2025Article
- Chest CT-determined sarcopenia is associated with poorer functional outcomes in osteoarthritis patients undergoing total knee arthroplasty: a retrospective cohort study.Scientific reports · 2025Article
- Based on CT scans at the 12th thoracic spine level, assessing the impact of skeletal muscle and adipose tissue index on one-year postoperative mortality in elderly hip fracture patients: a propensity score-matched multicenter retrospective study.BMC musculoskeletal disorders · 2025Article
- Association between CT-derived skeletal muscle and fat indices and fracture healing following operative treatment for intertrochanteric fractures: a multicenter retrospective study.Frontiers in nutrition · 2025Article
- Implant-related and medical complications in patients with sarcopenia undergoing total shoulder arthroplasty: A retrospective matched-cohort analysis.Shoulder & elbow · 2024Article
- The Negative Impacts of Sarcopenia on Primary Total Knee Arthroplasty under the Enhanced Recovery after Surgery Protocol.Orthopaedic surgery · 2024Article
- Sex Differences in Sarcopenia in Patients Undergoing Total Knee Arthroplasty for Advanced Knee Osteoarthritis.Medicina (Kaunas, Lithuania) · 2024Article
- No Blood Loss Increase in Cementless vs. Cemented Fixation Following Bilateral Total Knee Arthroplasty: A Propensity Score Matching Study.Medicina (Kaunas, Lithuania) · 2023Article
- Self-reported difficulty in walking 400 meters: the "red flag" for probable sarcopenia.BMC geriatrics · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSarcopenia, an age-related loss of skeletal muscle mass and function, is correlated with adverse outcomes after some surgeries. This study examined the characteristics of sarcopenic patients undergoing primary total knee arthroplasty (TKA), and identified low muscle mass as an independent risk factor for postoperative TKA complications.
methodsA retrospective cohort study examined 452 patients who underwent TKA. The skeletal muscle index (SMI) was obtained via bioelectrical impedance analysis (BIA), along with demographics, the Charlson Comorbidity Index, and medication, laboratory and operative data for 2018-2021. Patients were categorized into normal (n = 417) and sarcopenic (n = 35) groups using the SMI cut-off suggested by the Asian Working Group for Sarcopenia 2019 (males, < 7.0 kg/m
resultsThe proportion of sarcopenic patients in primary TKA was 7.7% (35/452). The sarcopenic group had a lower preoperative haemoglobin (12.18 ± 1.20 vs. 13.04 ± 1.73 g/dL, p = 0.004) and total protein (6.73 ± 0.42 vs. 7.06 ± 0.44 mg/dL, p = 0.001). Propensity scoring matching and logistic regression showed that more patients in the sarcopenic group received postoperative blood transfusions (OR = 6.60, 95% CI: 1.57-45.5, p = 0.021); there was no significant difference in AKI or delirium. Univariate receiver operating characteristic curve analysis of the propensity-matched group, to determine the predictive value of SMI for postoperative transfusion, gave an AUC of 0.797 (0.633-0.96) and SMI cut-off of 5.6 kg/m
conclusionsLow muscle mass determined by BIA was an independent risk factor for postoperative transfusion in TKA. Multifrequency BIA can serve as a screening tool for sarcopenia that may influence the orthopaedic decision-making process or treatment planning in patients with sarcopenia undergoing primary TKA. LEVEL OF EVIDENCE: III, retrospective cohort study.
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