Evidence map›Paper›PMID 35296155›Full record

ArticleHypertension (Dallas, Tex. : 1979)2022

Na

Chuanming Xu, Guangrui Yang, Ziwei Fu, Yanting Chen, Shiying Xie, Fei Wang, Tianxin Yang

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Biomolecules · 2026
    Article
  3. Article
  4. Kidney Renin-Angiotensin System: Lost in a RAS Cascade.Hypertension (Dallas, Tex. : 1979) · 2024
    Article
  5. Review
  6. Article
  7. The Epithelial Sodium Channel-An Underestimated Drug Target.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chuanming XuDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.ORCID 0000-0001-7082-2833
Guangrui YangDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.
Ziwei FuDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.
Yanting ChenDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.ORCID 0000-0002-5041-9796
Shiying XieDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.
Fei WangDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.ORCID 0000-0001-8405-3561
Tianxin YangDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City.ORCID 0000-0003-4209-2284
University of Utah · US

Funding

Interaction of PGE2 and intrarenal RAS in AngII-induced hypertensionR01DK104072 · NIDDK · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI YANG, TIANXIN · 2015 to 2025
$3.7M
Role of (pro)renin receptor in aldosterone signaling in the kidneyR01HL139689 · NHLBI · UNIVERSITY OF UTAH · PI YANG, TIANXIN · 2018 to 2021
$2.3M
Interaction of (pro)renin receptor and PPARy in regulation of plasma volumeR01HL135851 · NHLBI · UNIVERSITY OF UTAH · PI YANG, TIANXIN · 2017 to 2021
$2.3M
Role of CTRP1 in Renal Sodium Handling in Obesity-Related HypertensionK99HL155850 · NHLBI · UNIVERSITY OF UTAH · PI WANG, FEI · 2021 to 2022
$180k
The function and regulation of intrarenal aldosterone synthase in ischemia-induced hypertension and renal injuryI01BX004871 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI Tianxin Yang · 2021 to 2026
–
BLR&D Research Career Scientist Award ApplicationIK6BX005223 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI YANG, TIANXIN · 2021 to 2025
–
BLRD VA I01 BX004871BLRD VA IK6 BX005223NHLBI NIH HHS K99 HL155850NHLBI NIH HHS R01 HL135851NHLBI NIH HHS R01 HL139689NIDDK NIH HHS R01 DK104072
6 · The paper itself

Abstract

backgroundThe collecting duct (CD) is a major site of both biosynthesis and action of prostaglandin E

methodsMice with Aqp2Cre-driven deletion of COX-2 (COX-2

resultsFollowing 28-day LS intake, COX-2

conclusionsThe study for the first time reports that CD COX-2/EP

Indexed as

ReninRenin-Angiotensin SystemAldosteroneAnimalsCyclooxygenase 2Epithelial Sodium ChannelsMiceProstaglandinsAldosteroneCyclooxygenase 2Epithelial Sodium ChannelsProstaglandinsRenincollecting ductcyclooxygenase-2EP1 receptorlow saltrenin-angiotensin system

Identifiers

PMID35296155
PMCPMC9212212
OpenAlexW4220713054

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.