Evidence map›Paper›PMID 35296089›Full record

ArticleFrontiers in immunology2022

Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection.

Demo Yemane Tesfaye, Sonja Bobic, Anna Lysén, Peter Csaba Huszthy, Arnar Gudjonsson, Ranveig Braathen, Bjarne Bogen, Even Fossum

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Demo Yemane TesfayeDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Sonja BobicDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Anna LysénDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Peter Csaba HuszthyDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Arnar GudjonssonDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Ranveig BraathenDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Bjarne BogenDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Even FossumDepartment of Immunology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting antigen to conventional dendritic cells (cDCs) can improve antigen-specific immune responses and additionally be used to influence the polarization of the immune responses. However, the mechanisms by which this is achieved are less clear. To improve our understanding, we here evaluate molecular and cellular requirements for CD4

Indexed as

Influenza, HumanInfluenza VaccinesAnimalsAntibody FormationAntigensDendritic CellsHumansImmunoglobulin GInterleukin-12MiceAntigensImmunoglobulin GInfluenza VaccinesInterleukin-12dendritic cellsIgG2atargetingTh1XCR1

Identifiers

PMID35296089
PMCPMC8918470
OpenAlexW4214677968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.