ArticleFrontiers in public health2022
Relationship Between Dry Eye Disease and Emotional Disorder: The Mediating Effect of Health Anxiety.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Okra eyelid patch versus sodium hyaluronate combined with ofloxacin eye drop in the treatment of meibomian gland dysfunction: a randomized controlled trial.BMC ophthalmology · 2026Trial
- Laughter Exercise for Symptomatic Improvement in Dry Eye Following Cataract Surgery: A Randomized Controlled Trial.Clinical ophthalmology (Auckland, N.Z.) · 2026Trial
- Recombinant human nerve growth factor (cenegermin) for moderate-to-severe dry eye: phase II, randomized, vehicle-controlled, dose-ranging trial.BMC ophthalmology · 2024Trial
- Apparent protective associations between smoking, alcohol consumption, and dry eye disease: evidence from a community-based Adult Dry Eye Cohort (ADEC) in Beijing.BMC public health · 2026Article
- Correlation of ocular surface function with sleep quality, anxiety, and depression in patients with dry eye disease.World journal of psychiatry · 2026Article
- Dry Eye Disease and Psychiatric Disorders: Neuroimmune Mechanisms and Therapeutic Perspectives.International journal of molecular sciences · 2025Review
- The relationship between subthreshold anxiety disorder and symptoms and signs of dry eye disease.Scientific reports · 2025Article
- Prevalence of depression and anxiety and related influencing factors in the Chinese population with noncommunicable chronic diseases: A network perspective.World journal of psychiatry · 2025Article
- Clinical Characterization of the Lacrimal Functional Unit in Patients with Chronic Ocular Pain Associated with Dry Eye Disease.Journal of clinical medicine · 2025Article
- Associations Between Dry Eye Disease and Mental Health Conditions in the All of Us Research Program.American journal of ophthalmology · 2025Article
- Evaluation of dry eye disease symptomatology and mental health status among patients with different COVID-19 statuses.International journal of ophthalmology · 2024Article
- Prevalence of Dry Eye Symptoms and Associated Risk Factors among University Students in Poland.International journal of environmental research and public health · 2023Article
- Depression and anxiety of medical students at Kunming Medical University during COVID-19: A cross-sectional survey.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to investigate the relationship between dry eye disease (DED) and anxiety, as well as DED and depression. Additionally, the influence of health anxiety (HA) on this relationship was determined. Methods: A total of 206 patients with DED were recruited from Tianjin Medical University Eye Hospital clinic and surveyed using demographic questionnaires, the Ocular Surface Disease Index (OSDI), Hospital Anxiety and Depression Scale (HADS), and Short Health Anxiety Inventory (SHAI). Additionally, they were examined using Keratograph 5M and assessed for DED by corneal fluorescein staining. Regression analysis and the bootstrap method were used to investigate the influence of HA on the relationship between DED and emotional disorders. Results: Among the 206 patients with DED, 52 (25.24%) and 56 (27.18%) patients showed depression and anxiety, respectively. The OSDI score and HA were positively correlated with depression and anxiety ( Conclusions: We found a significant correlation between DED and anxiety and depression. Moreover, HA was a mediator of the relationship between DED symptoms and anxiety and depression.
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