Evidence map›Paper›PMID 35295882›Full record

ArticleFrontiers in human neuroscience2022

Forgiveness Mediates the Relationship Between Middle Frontal Gyrus Volume and Clinical Symptoms in Adolescents.

Eleanor M Schuttenberg, Jennifer T Sneider, David H Rosmarin, Julia E Cohen-Gilbert, Emily N Oot, Anna M Seraikas, Elena R Stein, Arkadiy L Maksimovskiy, Sion K Harris, Marisa M Silveri

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Forgiveness and transgression-related rumination in perimenopausal depression: a testable socio-affective hypothesis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Article
  3. Article
  4. The virtue of temperance: a neurobiological perspective.Frontiers in human neuroscience · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eleanor M SchuttenbergNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.
Jennifer T SneiderNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.
David H RosmarinDepartment of Psychiatry and Harvard Medical School, Harvard University, Boston, MA, United States.
Julia E Cohen-GilbertNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.
Emily N OotNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.
Anna M SeraikasNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.
Elena R SteinNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.
Arkadiy L MaksimovskiyBrain Imaging Center, McLean Hospital, Belmont, MA, United States.
Sion K HarrisCenter for Adolescent Behavioral Health Research, Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, MA, United States.
Marisa M SilveriNeurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dispositional forgiveness is positively associated with many facets of wellbeing and has protective implications against depression and anxiety in adolescents. However, little work has been done to examine neurobiological aspects of forgiveness as they relate to clinical symptoms. In order to better understand the neural mechanisms supporting the protective role of forgiveness in adolescents, the current study examined the middle frontal gyrus (MFG), which comprises the majority of the dorsolateral prefrontal cortex (DLPFC) and is associated with cognitive regulation, and its relationship to forgiveness and clinical symptoms in a sample of healthy adolescents. In this cross-sectional study (

Indexed as

adolescenceanxietydepressionforgivenessforgiveness and cortical volumemiddle frontal gyrusstructural MRI

Identifiers

PMID35295882
PMCPMC8918469

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.