Evidence map›Paper›PMID 35295617›Full record

ArticlePhotoacoustics2022

Monitoring peripheral hemodynamic response to changes in blood pressure via photoacoustic imaging.

Yash Mantri, Tyler R Dorobek, Jason Tsujimoto, William F Penny, Pranav S Garimella, Jesse V Jokerst

Open access · goldAbstract read
In one paragraph

Article in Photoacoustics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  6. Review
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  8. Review
  9. Dual-Scan Photoacoustic Tomography for the Imaging of Vascular Structure on Foot.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yash MantriDepartment of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Tyler R DorobekDepartment of Nanoengineering, University of California San Diego, La Jolla, CA, USA.
Jason TsujimotoDepartment of Bioengineering, University of California San Diego, La Jolla, CA, USA.
William F PennyDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Pranav S GarimellaDepartment of Nephrology - Hypertension, School of Medicine, University of California San Diego, La Jolla, CA, USA.
Jesse V JokerstDepartment of Nanoengineering, University of California San Diego, La Jolla, CA, USA.
University of California, San Diego · USLa Jolla Bioengineering Institute · US

Funding

Tubular secretion, kidney disease progression, and drug dosing in older adultsK23DK114556 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARIMELLA, PRANAV · 2018 to 2022
$1.0M
Non-Invasive Detection and Staging of Decubitus and Diabetic UlcersR21AG065776 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2021
$575k
NIA NIH HHS R21 AG065776NIDDK NIH HHS K23 DK114556
6 · The paper itself

Abstract

Chronic wounds and amputations are common in chronic kidney disease patients needing hemodialysis (HD). HD is often complicated by drops in blood pressure (BP) called intra-dialytic hypotension. Whether intra-dialytic hypotension is associated with detectable changes in foot perfusion, a risk factor for wound formation and impaired healing remains unknown. Photoacoustic (PA) imaging is ideally suited to study perfusion changes. We scanned the feet of 20 HD and 11 healthy subjects. HD patients were scanned before and after a dialysis session whereas healthy subjects were scanned twice at rest and once after a 10 min exercise period while BP was elevated. Healthy (r = 0.70, p < 0.0001) and HD subjects (r = 0.43, p < 0.01) showed a significant correlation between PA intensity and systolic BP. Furthermore, HD cohort showed a significantly reduced PA response to changes in BP compared to the healthy controls (p < 0.0001), showing that PA can monitor hemodynamic changes due to changes in BP.

Indexed as

Blood pressureBP, Blood pressureChronic kidney diseaseCKD, Chronic kidney diseaseDialysisESKD, End stage kidney diseasefMRI, Functional magnetic resonance imagingHD, HemodialysisHypertensionLDI, Laser doppler imagingOptoacoustic imagingPerfusionTcOM, Transcutaneous oxygen monitoring

Identifiers

PMID35295617
PMCPMC8918860
OpenAlexW4220787785

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.