ReviewExposome2022
An exposomic framework to uncover environmental drivers of aging.
Review in Exposome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Meta-ERS: an exposome-based risk score using non-genetic factors to guide osteoporosis prevention.Journal of translational medicine · 2026Article
- A nutrient-wide analysis of the associations of dietary nutrients with all-cause and disease-specific mortality.BMC public health · 2026Article
- Review
- Integrating the environmental and genetic architectures of aging and mortality.Nature medicine · 2025Article
- Global research trends on the human exposome: a bibliometric analysis (2005-2024).Environmental science and pollution research international · 2025Review
- The role of residual (veterinary) antibiotics in chemical exposome analysis: Current progress and future perspectives.Comprehensive reviews in food science and food safety · 2025Review
- Leveraging Administrative Health Databases to Address Health Challenges in Farming Populations: Scoping Review and Bibliometric Analysis (1975-2024).JMIR public health and surveillance · 2025Article
- Exposome on skeletal muscle system: a mini-review.European journal of applied physiology · 2024Review
- Assessing household lifestyle exposures from consumer purchases, the My Purchases cohort.Scientific reports · 2023Article
- Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.GeroScience · 2023Review
- To promote healthy aging, focus on the environment.Nature aging · 2023Review
- Invited Perspective: Mixtures-Are They Worth the Risk (Assessment)?Environmental health perspectives · 2023Article
- Editorial: Healthspan and neural aging: Merging the exposome and one environmental health - From molecular mechanisms to epidemiology.Frontiers in aging neuroscience · 2023Article
- Linking Air Pollution Exposure to Blood-Based Metabolic Features in a Community-Based Aging Cohort with and without Dementia.Journal of Alzheimer's disease : JAD · 2023Article
- Dynamic neurocognitive adaptation: A follow-up exposome investigation in aging.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The exposome, the environmental complement of the genome, is an omics level characterization of an individual's exposures. There is growing interest in uncovering the role of the environment in human health using an exposomic framework that provides a systematic and unbiased analysis of the non-genetic drivers of health and disease. Many environmental toxicants are associated with molecular hallmarks of aging. An exposomic framework has potential to advance understanding of these associations and how modifications to the environment can promote healthy aging in the population. However, few studies have used this framework to study biological aging. We provide an overview of approaches and challenges in using an exposomic framework to investigate environmental drivers of aging. While capturing exposures over a life course is a daunting and expensive task, the use of historical data can be a practical way to approach this research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.