Evidence map›Paper›PMID 35295484›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2021

The Role of PIEZO1 in Urinary Bladder Function and Dysfunction in a Rodent Model of Cyclophosphamide-Induced Cystitis.

Katharine I K Beča, Beatrice M Girard, Thomas J Heppner, Grant W Hennig, Gerald M Herrera, Mark T Nelson, Margaret A Vizzard

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Lipid Regulation of Mechanosensitive Ion Channels.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Pharmacology of PIEZO1 channels.British journal of pharmacology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Katharine I K BečaDepartment of Neurological Sciences, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Beatrice M GirardDepartment of Neurological Sciences, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Thomas J HeppnerDepartment of Pharmacology, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Grant W HennigDepartment of Pharmacology, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Gerald M HerreraDepartment of Pharmacology, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Mark T NelsonDepartment of Pharmacology, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
Margaret A VizzardDepartment of Neurological Sciences, The Larner College of Medicine, University of Vermont, Burlington, VT, United States.
University of Vermont · US

Funding

How is Fullness Sensed in the Urinary Bladder?R01DK125543 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HEPPNER, THOMAS, HERRERA, GERALD M. · 2020 to 2024
$2.2M
NIDDK NIH HHS R01 DK125543
6 · The paper itself

Abstract

In the urinary bladder, mechanosensitive ion channels (MSCs) underlie the transduction of bladder stretch into sensory signals that are relayed to the PNS and CNS. PIEZO1 is a recently identified MSC that is Ca

Indexed as

calcium signalinginterstitial cystitis (IC)/bladder pain syndrome (BPS)mechanosensationmicturitionPIEZO1

Identifiers

PMID35295484
PMCPMC8915741
OpenAlexW3206839583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.