Evidence map›Paper›PMID 35295235›Full record

ArticleERJ open research2022

Novel volumetric capnography indices measure ventilation inhomogeneity in cystic fibrosis.

Sotirios Fouzas, Anne-Christianne Kentgens, Olga Lagiou, Bettina Sarah Frauchiger, Florian Wyler, Ilias Theodorakopoulos, Sophie Yammine, Philipp Latzin

Abstract read
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Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sotirios FouzasPaediatric Respiratory Unit, University Hospital of Patras, Patras, Greece.
Anne-Christianne KentgensDivision of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Olga LagiouPaediatric Respiratory Unit, University Hospital of Patras, Patras, Greece.
Bettina Sarah FrauchigerDivision of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Florian WylerDivision of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Ilias TheodorakopoulosPaediatric Respiratory Unit, University Hospital of Patras, Patras, Greece.
Sophie YammineDivision of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Philipp LatzinDivision of Paediatric Respiratory Medicine and Allergology, Dept of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.ORCID https://orcid.org/0000-0002-5239-1571

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Volumetric capnography (VCap) is a simpler alternative to multiple-breath washout (MBW) to detect ventilation inhomogeneity in patients with cystic fibrosis (CF). However, its diagnostic performance is influenced by breathing dynamics. We introduce two novel VCap indices, the capnographic inhomogeneity indices (CIIs), that may overcome this limitation and explore their diagnostic characteristics in a cohort of CF patients. Methods: We analysed 320 N Results: Both CIIs were significantly higher in CF patients compared with controls (mean±sd CII Conclusion: CIIs detect ventilation inhomogeneity better than classical VCap indices and correlate well with LCI. However, further studies on their diagnostic performance and clinical utility are required.

Identifiers

PMID35295235
PMCPMC8918935

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