ArticleERJ open research2022
Assessing cough symptom severity in refractory or unexplained chronic cough: findings from patient focus groups and an international expert panel.
Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 27 citations in OpenAlex.
- Psychometric validation of the severity of chronic cough diary, leicester cough questionnaire, and a cough severity visual analogue scale in patients with refractory chronic cough.Journal of patient-reported outcomes · 2025Trial
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- Measuring the effect of azithromycin in chronic respiratory disease using continuous cough monitoring: an open-label exploratory trial.ERJ open research · 2026Article
- Unmet need for biomarkers in chronic cough: a review of current challenges and future directions.ERJ open research · 2025Review
- The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study.ERJ open research · 2025Article
- Top 10 priorities for chronic cough: Canadian James Lind Alliance Priority-Setting Partnership (CAN-COUGH).ERJ open research · 2025Article
- The McMaster Cough Severity Questionnaire (MCSQ): a cough severity instrument for patients with refractory chronic cough.The European respiratory journal · 2025Article
- Recruiting participants for focus groups in health research: a meta-research study.BMC medical research methodology · 2025Article
- An exploration of clinically meaningful definitions of cough bouts.ERJ open research · 2024Article
- Patient-reported assessments of chronic cough in clinical trials: accessory or primary endpoints?Journal of thoracic disease · 2024Review
- Exploring the concept of disease control in chronic cough.ERJ open research · 2024Article
- Development and validation of a novel questionnaire to describe and assess sensations and triggers associated with refractory and unexplained chronic cough.BMJ open respiratory research · 2024Article
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- Article
- Article
- Methods of Cough Assessment and Objectivization.Physiological research · 2023Review
- Article
- Understanding patient experience of chronic cough in interstitial lung disease.ERJ open research · 2023Article
- The "vicious circle" of chronic cough: the patient experience - qualitative synthesis.ERJ open research · 2023Review
- Article
Corrections and comments
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Authors and funding
21 authors at 15 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cough symptom severity represents an important subjective end-point to assess the impact of therapies for patients with refractory or unexplained chronic cough (RCC/UCC). As existing instruments assessing the severity of cough are neither widely available nor tested for measurement properties, we aim to develop a new patient-reported outcome measure addressing cough severity. Objective: The aim of this study was to establish items and domains that would inform development of a new cough severity instrument. Methods: Three focus groups involving 16 adult patients with RCC/UCC provided data that we analysed using directed content analysis. Discussions led to consensus among an international panel of 15 experts on candidate items and domains to assess cough severity. Results: The patient focus group provided 48 unique items arranged under broad domains of urge-to-cough sensations and cough symptom. Feedback from expert panel members confirmed the appropriateness of items and domains, and provided an additional subdomain related to cough triggers. The final conceptual framework comprised 51 items in the following domains: urge-to-cough sensations (subdomains: frequency and intensity) and cough symptom (subdomains: triggers, control, frequency, fit/bout duration, intensity, quality and associated features/sequelae). Conclusions: Consensus findings from patients and international experts established domains of urge-to-cough and cough symptom with associated subdomains and relevant items. The results support item generation and content validity for a novel patient-reported outcome measure for use in health research and clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.